R-universe search: needs:plyr

topepo

caret:Classification and Regression Training

Misc functions for training and plotting classification and regression models.

Maintained by Max Kuhn. Last updated 4 months ago.

1.6k stars 19.24 score 61k scripts 303 dependents

hadley

reshape2:Flexibly Reshape Data: A Reboot of the Reshape Package

Flexibly restructure and aggregate data using just two functions: melt and 'dcast' (or 'acast').

Maintained by Hadley Wickham. Last updated 4 years ago.

cpp

210 stars 17.19 score 94k scripts 2.0k dependents

bioc

clusterProfiler:A universal enrichment tool for interpreting omics data

This package supports functional characteristics of both coding and non-coding genomics data for thousands of species with up-to-date gene annotation. It provides a univeral interface for gene functional annotation from a variety of sources and thus can be applied in diverse scenarios. It provides a tidy interface to access, manipulate, and visualize enrichment results to help users achieve efficient data interpretation. Datasets obtained from multiple treatments and time points can be analyzed and compared in a single run, easily revealing functional consensus and differences among distinct conditions.

Maintained by Guangchuang Yu. Last updated 4 months ago.

annotation clustering genesetenrichment go kegg multiplecomparison pathways reactome visualization enrichment-analysis gsea

1.1k stars 17.03 score 11k scripts 48 dependents

satijalab

Seurat:Tools for Single Cell Genomics

A toolkit for quality control, analysis, and exploration of single cell RNA sequencing data. 'Seurat' aims to enable users to identify and interpret sources of heterogeneity from single cell transcriptomic measurements, and to integrate diverse types of single cell data. See Satija R, Farrell J, Gennert D, et al (2015) <doi:10.1038/nbt.3192>, Macosko E, Basu A, Satija R, et al (2015) <doi:10.1016/j.cell.2015.05.002>, Stuart T, Butler A, et al (2019) <doi:10.1016/j.cell.2019.05.031>, and Hao, Hao, et al (2020) <doi:10.1101/2020.10.12.335331> for more details.

Maintained by Paul Hoffman. Last updated 1 years ago.

human-cell-atlas single-cell-genomics single-cell-rna-seq cpp

2.4k stars 16.86 score 50k scripts 73 dependents

stan-dev

bayesplot:Plotting for Bayesian Models

Plotting functions for posterior analysis, MCMC diagnostics, prior and posterior predictive checks, and other visualizations to support the applied Bayesian workflow advocated in Gabry, Simpson, Vehtari, Betancourt, and Gelman (2019) <doi:10.1111/rssa.12378>. The package is designed not only to provide convenient functionality for users, but also a common set of functions that can be easily used by developers working on a variety of R packages for Bayesian modeling, particularly (but not exclusively) packages interfacing with 'Stan'.

Maintained by Jonah Gabry. Last updated 2 months ago.

bayesian ggplot2 mcmc pandoc stan statistical-graphics visualization

436 stars 16.69 score 6.5k scripts 98 dependents

paul-buerkner

brms:Bayesian Regression Models using 'Stan'

Fit Bayesian generalized (non-)linear multivariate multilevel models using 'Stan' for full Bayesian inference. A wide range of distributions and link functions are supported, allowing users to fit -- among others -- linear, robust linear, count data, survival, response times, ordinal, zero-inflated, hurdle, and even self-defined mixture models all in a multilevel context. Further modeling options include both theory-driven and data-driven non-linear terms, auto-correlation structures, censoring and truncation, meta-analytic standard errors, and quite a few more. In addition, all parameters of the response distribution can be predicted in order to perform distributional regression. Prior specifications are flexible and explicitly encourage users to apply prior distributions that actually reflect their prior knowledge. Models can easily be evaluated and compared using several methods assessing posterior or prior predictions. References: Bürkner (2017) <doi:10.18637/jss.v080.i01>; Bürkner (2018) <doi:10.32614/RJ-2018-017>; Bürkner (2021) <doi:10.18637/jss.v100.i05>; Carpenter et al. (2017) <doi:10.18637/jss.v076.i01>.

Maintained by Paul-Christian Bürkner. Last updated 2 days ago.

bayesian-inference brms multilevel-models stan statistical-models

1.3k stars 16.62 score 13k scripts 35 dependents

ggobi

GGally:Extension to 'ggplot2'

The R package 'ggplot2' is a plotting system based on the grammar of graphics. 'GGally' extends 'ggplot2' by adding several functions to reduce the complexity of combining geometric objects with transformed data. Some of these functions include a pairwise plot matrix, a two group pairwise plot matrix, a parallel coordinates plot, a survival plot, and several functions to plot networks.

Maintained by Barret Schloerke. Last updated 11 months ago.

597 stars 16.15 score 17k scripts 154 dependents

bioc

enrichplot:Visualization of Functional Enrichment Result

The 'enrichplot' package implements several visualization methods for interpreting functional enrichment results obtained from ORA or GSEA analysis. It is mainly designed to work with the 'clusterProfiler' package suite. All the visualization methods are developed based on 'ggplot2' graphics.

Maintained by Guangchuang Yu. Last updated 3 months ago.

annotation genesetenrichment go kegg pathways software visualization enrichment-analysis pathway-analysis

239 stars 15.71 score 3.1k scripts 58 dependents

stan-dev

rstanarm:Bayesian Applied Regression Modeling via Stan

Estimates previously compiled regression models using the 'rstan' package, which provides the R interface to the Stan C++ library for Bayesian estimation. Users specify models via the customary R syntax with a formula and data.frame plus some additional arguments for priors.

Maintained by Ben Goodrich. Last updated 15 days ago.

bayesian bayesian-data-analysis bayesian-inference bayesian-methods bayesian-statistics multilevel-models rstan rstanarm stan statistical-modeling cpp

393 stars 15.70 score 5.0k scripts 13 dependents

njtierney

naniar:Data Structures, Summaries, and Visualisations for Missing Data

Missing values are ubiquitous in data and need to be explored and handled in the initial stages of analysis. 'naniar' provides data structures and functions that facilitate the plotting of missing values and examination of imputations. This allows missing data dependencies to be explored with minimal deviation from the common work patterns of 'ggplot2' and tidy data. The work is fully discussed at Tierney & Cook (2023) <doi:10.18637/jss.v105.i07>.

Maintained by Nicholas Tierney. Last updated 21 days ago.

data-visualisation ggplot2 missing-data missingness tidy-data

657 stars 15.63 score 5.1k scripts 9 dependents

hms-dbmi

UpSetR:A More Scalable Alternative to Venn and Euler Diagrams for Visualizing Intersecting Sets

Creates visualizations of intersecting sets using a novel matrix design, along with visualizations of several common set, element and attribute related tasks (Conway 2017) <doi:10.1093/bioinformatics/btx364>.

Maintained by Jake Conway. Last updated 4 years ago.

gehlenborglab ggplot2 upset upsetr visualization

781 stars 15.33 score 4.8k scripts 42 dependents

xrobin

pROC:Display and Analyze ROC Curves

Tools for visualizing, smoothing and comparing receiver operating characteristic (ROC curves). (Partial) area under the curve (AUC) can be compared with statistical tests based on U-statistics or bootstrap. Confidence intervals can be computed for (p)AUC or ROC curves.

Maintained by Xavier Robin. Last updated 5 months ago.

bootstrapping covariance hypothesis-testing machine-learning plot plotting roc roc-curve variance cpp

125 stars 15.18 score 16k scripts 445 dependents

bioc

DOSE:Disease Ontology Semantic and Enrichment analysis

This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.

Maintained by Guangchuang Yu. Last updated 5 months ago.

annotation visualization multiplecomparison genesetenrichment pathways software disease-ontology enrichment-analysis semantic-similarity

119 stars 14.97 score 2.0k scripts 61 dependents

florianhartig

DHARMa:Residual Diagnostics for Hierarchical (Multi-Level / Mixed) Regression Models

The 'DHARMa' package uses a simulation-based approach to create readily interpretable scaled (quantile) residuals for fitted (generalized) linear mixed models. Currently supported are linear and generalized linear (mixed) models from 'lme4' (classes 'lmerMod', 'glmerMod'), 'glmmTMB', 'GLMMadaptive', and 'spaMM'; phylogenetic linear models from 'phylolm' (classes 'phylolm' and 'phyloglm'); generalized additive models ('gam' from 'mgcv'); 'glm' (including 'negbin' from 'MASS', but excluding quasi-distributions) and 'lm' model classes. Moreover, externally created simulations, e.g. posterior predictive simulations from Bayesian software such as 'JAGS', 'STAN', or 'BUGS' can be processed as well. The resulting residuals are standardized to values between 0 and 1 and can be interpreted as intuitively as residuals from a linear regression. The package also provides a number of plot and test functions for typical model misspecification problems, such as over/underdispersion, zero-inflation, and residual spatial, phylogenetic and temporal autocorrelation.

Maintained by Florian Hartig. Last updated 30 days ago.

glmm regression regression-diagnostics residual

226 stars 14.74 score 2.8k scripts 10 dependents

dcomtois

summarytools:Tools to Quickly and Neatly Summarize Data

Data frame summaries, cross-tabulations, weight-enabled frequency tables and common descriptive (univariate) statistics in concise tables available in a variety of formats (plain ASCII, Markdown and HTML). A good point-of-entry for exploring data, both for experienced and new R users.

Maintained by Dominic Comtois. Last updated 2 days ago.

descriptive-statistics frequency-table html-report markdown pander pandoc pandoc-markdown rmarkdown rstudio

528 stars 14.69 score 2.9k scripts 6 dependents

bioc

TCGAbiolinks:TCGAbiolinks: An R/Bioconductor package for integrative analysis with GDC data

The aim of TCGAbiolinks is : i) facilitate the GDC open-access data retrieval, ii) prepare the data using the appropriate pre-processing strategies, iii) provide the means to carry out different standard analyses and iv) to easily reproduce earlier research results. In more detail, the package provides multiple methods for analysis (e.g., differential expression analysis, identifying differentially methylated regions) and methods for visualization (e.g., survival plots, volcano plots, starburst plots) in order to easily develop complete analysis pipelines.

Maintained by Tiago Chedraoui Silva. Last updated 1 months ago.

dnamethylation differentialmethylation generegulation geneexpression methylationarray differentialexpression pathways network sequencing survival software bioc bioconductor gdc integrative-analysis tcga tcga-data tcgabiolinks

310 stars 14.47 score 1.6k scripts 6 dependents

indrajeetpatil

ggstatsplot:'ggplot2' Based Plots with Statistical Details

Extension of 'ggplot2', 'ggstatsplot' creates graphics with details from statistical tests included in the plots themselves. It provides an easier syntax to generate information-rich plots for statistical analysis of continuous (violin plots, scatterplots, histograms, dot plots, dot-and-whisker plots) or categorical (pie and bar charts) data. Currently, it supports the most common types of statistical approaches and tests: parametric, nonparametric, robust, and Bayesian versions of t-test/ANOVA, correlation analyses, contingency table analysis, meta-analysis, and regression analyses. References: Patil (2021) <doi:10.21105/joss.03236>.

Maintained by Indrajeet Patil. Last updated 1 months ago.

bayes-factors datascience dataviz effect-size ggplot-extension hypothesis-testing non-parametric-statistics regression-models statistical-analysis

2.1k stars 14.46 score 3.0k scripts 1 dependents

singmann

afex:Analysis of Factorial Experiments

Convenience functions for analyzing factorial experiments using ANOVA or mixed models. aov_ez(), aov_car(), and aov_4() allow specification of between, within (i.e., repeated-measures), or mixed (i.e., split-plot) ANOVAs for data in long format (i.e., one observation per row), automatically aggregating multiple observations per individual and cell of the design. mixed() fits mixed models using lme4::lmer() and computes p-values for all fixed effects using either Kenward-Roger or Satterthwaite approximation for degrees of freedom (LMM only), parametric bootstrap (LMMs and GLMMs), or likelihood ratio tests (LMMs and GLMMs). afex_plot() provides a high-level interface for interaction or one-way plots using ggplot2, combining raw data and model estimates. afex uses type 3 sums of squares as default (imitating commercial statistical software).

Maintained by Henrik Singmann. Last updated 7 months ago.

124 stars 14.43 score 1.4k scripts 15 dependents

r-spatial

mapview:Interactive Viewing of Spatial Data in R

Quickly and conveniently create interactive visualisations of spatial data with or without background maps. Attributes of displayed features are fully queryable via pop-up windows. Additional functionality includes methods to visualise true- and false-color raster images and bounding boxes.

Maintained by Tim Appelhans. Last updated 3 months ago.

gis leaflet maps spatial visualization web-mapping

526 stars 14.39 score 7.3k scripts 27 dependents

bioc

xcms:LC-MS and GC-MS Data Analysis

Framework for processing and visualization of chromatographically separated and single-spectra mass spectral data. Imports from AIA/ANDI NetCDF, mzXML, mzData and mzML files. Preprocesses data for high-throughput, untargeted analyte profiling.

Maintained by Steffen Neumann. Last updated 20 days ago.

immunooncology massspectrometry metabolomics bioconductor feature-detection mass-spectrometry peak-detection cpp

196 stars 14.31 score 984 scripts 11 dependents

talgalili

heatmaply:Interactive Cluster Heat Maps Using 'plotly' and 'ggplot2'

Create interactive cluster 'heatmaps' that can be saved as a stand- alone HTML file, embedded in 'R Markdown' documents or in a 'Shiny' app, and available in the 'RStudio' viewer pane. Hover the mouse pointer over a cell to show details or drag a rectangle to zoom. A 'heatmap' is a popular graphical method for visualizing high-dimensional data, in which a table of numbers are encoded as a grid of colored cells. The rows and columns of the matrix are ordered to highlight patterns and are often accompanied by 'dendrograms'. 'Heatmaps' are used in many fields for visualizing observations, correlations, missing values patterns, and more. Interactive 'heatmaps' allow the inspection of specific value by hovering the mouse over a cell, as well as zooming into a region of the 'heatmap' by dragging a rectangle around the relevant area. This work is based on the 'ggplot2' and 'plotly.js' engine. It produces similar 'heatmaps' to 'heatmap.2' with the advantage of speed ('plotly.js' is able to handle larger size matrix), the ability to zoom from the 'dendrogram' panes, and the placing of factor variables in the sides of the 'heatmap'.

Maintained by Tal Galili. Last updated 9 months ago.

d3-heatmap dendextend dendrogram ggplot2 heatmap plotly

386 stars 14.21 score 2.0k scripts 45 dependents

dkahle

ggmap:Spatial Visualization with ggplot2

A collection of functions to visualize spatial data and models on top of static maps from various online sources (e.g Google Maps and Stamen Maps). It includes tools common to those tasks, including functions for geolocation and routing.

Maintained by David Kahle. Last updated 1 years ago.

770 stars 14.17 score 12k scripts 31 dependents

kassambara

factoextra:Extract and Visualize the Results of Multivariate Data Analyses

Provides some easy-to-use functions to extract and visualize the output of multivariate data analyses, including 'PCA' (Principal Component Analysis), 'CA' (Correspondence Analysis), 'MCA' (Multiple Correspondence Analysis), 'FAMD' (Factor Analysis of Mixed Data), 'MFA' (Multiple Factor Analysis) and 'HMFA' (Hierarchical Multiple Factor Analysis) functions from different R packages. It contains also functions for simplifying some clustering analysis steps and provides 'ggplot2' - based elegant data visualization.

Maintained by Alboukadel Kassambara. Last updated 5 years ago.

363 stars 14.13 score 15k scripts 52 dependents

bioc

qvalue:Q-value estimation for false discovery rate control

This package takes a list of p-values resulting from the simultaneous testing of many hypotheses and estimates their q-values and local FDR values. The q-value of a test measures the proportion of false positives incurred (called the false discovery rate) when that particular test is called significant. The local FDR measures the posterior probability the null hypothesis is true given the test's p-value. Various plots are automatically generated, allowing one to make sensible significance cut-offs. Several mathematical results have recently been shown on the conservative accuracy of the estimated q-values from this software. The software can be applied to problems in genomics, brain imaging, astrophysics, and data mining.

Maintained by John D. Storey. Last updated 5 months ago.

multiplecomparisons

116 stars 14.07 score 3.0k scripts 139 dependents

bioc

phyloseq:Handling and analysis of high-throughput microbiome census data

phyloseq provides a set of classes and tools to facilitate the import, storage, analysis, and graphical display of microbiome census data.

Maintained by Paul J. McMurdie. Last updated 5 months ago.

immunooncology sequencing microbiome metagenomics clustering classification multiplecomparison geneticvariability

600 stars 13.91 score 8.4k scripts 38 dependents

biomodhub

biomod2:Ensemble Platform for Species Distribution Modeling

Functions for species distribution modeling, calibration and evaluation, ensemble of models, ensemble forecasting and visualization. The package permits to run consistently up to 10 single models on a presence/absences (resp presences/pseudo-absences) dataset and to combine them in ensemble models and ensemble projections. Some bench of other evaluation and visualisation tools are also available within the package.

Maintained by Maya Guéguen. Last updated 21 hours ago.

95 stars 13.91 score 536 scripts 8 dependents

bioc

mixOmics:Omics Data Integration Project

Multivariate methods are well suited to large omics data sets where the number of variables (e.g. genes, proteins, metabolites) is much larger than the number of samples (patients, cells, mice). They have the appealing properties of reducing the dimension of the data by using instrumental variables (components), which are defined as combinations of all variables. Those components are then used to produce useful graphical outputs that enable better understanding of the relationships and correlation structures between the different data sets that are integrated. mixOmics offers a wide range of multivariate methods for the exploration and integration of biological datasets with a particular focus on variable selection. The package proposes several sparse multivariate models we have developed to identify the key variables that are highly correlated, and/or explain the biological outcome of interest. The data that can be analysed with mixOmics may come from high throughput sequencing technologies, such as omics data (transcriptomics, metabolomics, proteomics, metagenomics etc) but also beyond the realm of omics (e.g. spectral imaging). The methods implemented in mixOmics can also handle missing values without having to delete entire rows with missing data. A non exhaustive list of methods include variants of generalised Canonical Correlation Analysis, sparse Partial Least Squares and sparse Discriminant Analysis. Recently we implemented integrative methods to combine multiple data sets: N-integration with variants of Generalised Canonical Correlation Analysis and P-integration with variants of multi-group Partial Least Squares.

Maintained by Eva Hamrud. Last updated 6 days ago.

immunooncology microarray sequencing metabolomics metagenomics proteomics geneprediction multiplecomparison classification regression bioconductor genomics genomics-data genomics-visualization multivariate-analysis multivariate-statistics omics r-pkg r-project

185 stars 13.75 score 1.3k scripts 22 dependents

aphalo

ggpmisc:Miscellaneous Extensions to 'ggplot2'

Extensions to 'ggplot2' respecting the grammar of graphics paradigm. Statistics: locate and tag peaks and valleys; label plot with the equation of a fitted polynomial or other types of models; labels with P-value, R^2 or adjusted R^2 or information criteria for fitted models; label with ANOVA table for fitted models; label with summary for fitted models. Model fit classes for which suitable methods are provided by package 'broom' and 'broom.mixed' are supported. Scales and stats to build volcano and quadrant plots based on outcomes, fold changes, p-values and false discovery rates.

Maintained by Pedro J. Aphalo. Last updated 4 days ago.

data-analysis dataviz ggplot2-annotations ggplot2-stats statistics

107 stars 13.64 score 4.4k scripts 14 dependents

ropensci

taxize:Taxonomic Information from Around the Web

Interacts with a suite of web application programming interfaces (API) for taxonomic tasks, such as getting database specific taxonomic identifiers, verifying species names, getting taxonomic hierarchies, fetching downstream and upstream taxonomic names, getting taxonomic synonyms, converting scientific to common names and vice versa, and more. Some of the services supported include 'NCBI E-utilities' (<https://www.ncbi.nlm.nih.gov/books/NBK25501/>), 'Encyclopedia of Life' (<https://eol.org/docs/what-is-eol/data-services>), 'Global Biodiversity Information Facility' (<https://techdocs.gbif.org/en/openapi/>), and many more. Links to the API documentation for other supported services are available in the documentation for their respective functions in this package.

Maintained by Zachary Foster. Last updated 30 days ago.

taxonomy biology nomenclature json api web api-client identifiers species names api-wrapper biodiversity darwincore data taxize

274 stars 13.63 score 1.6k scripts 23 dependents

ropensci

rgbif:Interface to the Global Biodiversity Information Facility API

A programmatic interface to the Web Service methods provided by the Global Biodiversity Information Facility (GBIF; <https://www.gbif.org/developer/summary>). GBIF is a database of species occurrence records from sources all over the globe. rgbif includes functions for searching for taxonomic names, retrieving information on data providers, getting species occurrence records, getting counts of occurrence records, and using the GBIF tile map service to make rasters summarizing huge amounts of data.

Maintained by John Waller. Last updated 21 days ago.

gbif specimens api web-services occurrences species taxonomy biodiversity data lifewatch oscibio spocc

161 stars 13.26 score 2.1k scripts 20 dependents

bioc

dada2:Accurate, high-resolution sample inference from amplicon sequencing data

The dada2 package infers exact amplicon sequence variants (ASVs) from high-throughput amplicon sequencing data, replacing the coarser and less accurate OTU clustering approach. The dada2 pipeline takes as input demultiplexed fastq files, and outputs the sequence variants and their sample-wise abundances after removing substitution and chimera errors. Taxonomic classification is available via a native implementation of the RDP naive Bayesian classifier, and species-level assignment to 16S rRNA gene fragments by exact matching.

Maintained by Benjamin Callahan. Last updated 5 months ago.

immunooncology microbiome sequencing classification metagenomics amplicon bioconductor bioinformatics metabarcoding taxonomy cpp

487 stars 13.17 score 3.0k scripts 4 dependents

stan-dev

shinystan:Interactive Visual and Numerical Diagnostics and Posterior Analysis for Bayesian Models

A graphical user interface for interactive Markov chain Monte Carlo (MCMC) diagnostics and plots and tables helpful for analyzing a posterior sample. The interface is powered by the 'Shiny' web application framework from 'RStudio' and works with the output of MCMC programs written in any programming language (and has extended functionality for 'Stan' models fit using the 'rstan' and 'rstanarm' packages).

Maintained by Jonah Gabry. Last updated 3 years ago.

bayesian bayesian-data-analysis bayesian-inference bayesian-methods bayesian-statistics mcmc shiny-apps stan statistical-graphics

200 stars 13.13 score 1.6k scripts 15 dependents

bioc

ChIPseeker:ChIPseeker for ChIP peak Annotation, Comparison, and Visualization

This package implements functions to retrieve the nearest genes around the peak, annotate genomic region of the peak, statstical methods for estimate the significance of overlap among ChIP peak data sets, and incorporate GEO database for user to compare the own dataset with those deposited in database. The comparison can be used to infer cooperative regulation and thus can be used to generate hypotheses. Several visualization functions are implemented to summarize the coverage of the peak experiment, average profile and heatmap of peaks binding to TSS regions, genomic annotation, distance to TSS, and overlap of peaks or genes.

Maintained by Guangchuang Yu. Last updated 5 months ago.

annotation chipseq software visualization multiplecomparison atac-seq chip-seq comparison epigenetics epigenomics

233 stars 13.05 score 1.6k scripts 5 dependents

michaelhallquist

MplusAutomation:An R Package for Facilitating Large-Scale Latent Variable Analyses in Mplus

Leverages the R language to automate latent variable model estimation and interpretation using 'Mplus', a powerful latent variable modeling program developed by Muthen and Muthen (<https://www.statmodel.com>). Specifically, this package provides routines for creating related groups of models, running batches of models, and extracting and tabulating model parameters and fit statistics.

Maintained by Michael Hallquist. Last updated 16 hours ago.

86 stars 12.94 score 664 scripts 13 dependents

kassambara

ggcorrplot:Visualization of a Correlation Matrix using 'ggplot2'

The 'ggcorrplot' package can be used to visualize easily a correlation matrix using 'ggplot2'. It provides a solution for reordering the correlation matrix and displays the significance level on the plot. It also includes a function for computing a matrix of correlation p-values.

Maintained by Alboukadel Kassambara. Last updated 2 years ago.

190 stars 12.86 score 6.9k scripts 22 dependents

bioc

minfi:Analyze Illumina Infinium DNA methylation arrays

Tools to analyze & visualize Illumina Infinium methylation arrays.

Maintained by Kasper Daniel Hansen. Last updated 5 months ago.

immunooncology dnamethylation differentialmethylation epigenetics microarray methylationarray multichannel twochannel dataimport normalization preprocessing qualitycontrol

60 stars 12.82 score 996 scripts 27 dependents

bioc

MSnbase:Base Functions and Classes for Mass Spectrometry and Proteomics

MSnbase provides infrastructure for manipulation, processing and visualisation of mass spectrometry and proteomics data, ranging from raw to quantitative and annotated data.

Maintained by Laurent Gatto. Last updated 20 days ago.

immunooncology infrastructure proteomics massspectrometry qualitycontrol dataimport bioconductor bioinformatics mass-spectrometry proteomics-data visualisation cpp

131 stars 12.76 score 772 scripts 36 dependents

topepo

Cubist:Rule- And Instance-Based Regression Modeling

Regression modeling using rules with added instance-based corrections.

Maintained by Max Kuhn. Last updated 7 days ago.

40 stars 12.74 score 2.8k scripts 18 dependents

chr1swallace

coloc:Colocalisation Tests of Two Genetic Traits

Performs the colocalisation tests described in Giambartolomei et al (2013) <doi:10.1371/journal.pgen.1004383>, Wallace (2020) <doi:10.1371/journal.pgen.1008720>, Wallace (2021) <doi:10.1371/journal.pgen.1009440>, Pullin and Wallace (2025) <doi:10.1101/2024.08.21.608957>.

Maintained by Chris Wallace. Last updated 7 days ago.

164 stars 12.68 score 916 scripts 3 dependents

thibautjombart

adegenet:Exploratory Analysis of Genetic and Genomic Data

Toolset for the exploration of genetic and genomic data. Adegenet provides formal (S4) classes for storing and handling various genetic data, including genetic markers with varying ploidy and hierarchical population structure ('genind' class), alleles counts by populations ('genpop'), and genome-wide SNP data ('genlight'). It also implements original multivariate methods (DAPC, sPCA), graphics, statistical tests, simulation tools, distance and similarity measures, and several spatial methods. A range of both empirical and simulated datasets is also provided to illustrate various methods.

Maintained by Zhian N. Kamvar. Last updated 2 months ago.

182 stars 12.60 score 1.9k scripts 29 dependents

hrbrmstr

ggalt:Extra Coordinate Systems, 'Geoms', Statistical Transformations, Scales and Fonts for 'ggplot2'

A compendium of new geometries, coordinate systems, statistical transformations, scales and fonts for 'ggplot2', including splines, 1d and 2d densities, univariate average shifted histograms, a new map coordinate system based on the 'PROJ.4'-library along with geom_cartogram() that mimics the original functionality of geom_map(), formatters for "bytes", a stat_stepribbon() function, increased 'plotly' compatibility and the 'StateFace' open source font 'ProPublica'. Further new functionality includes lollipop charts, dumbbell charts, the ability to encircle points and coordinate-system-based text annotations.

Maintained by Bob Rudis. Last updated 2 years ago.

geom ggplot-extension ggplot2 ggplot2-geom ggplot2-scales

676 stars 12.60 score 2.3k scripts 7 dependents

inlabru-org

inlabru:Bayesian Latent Gaussian Modelling using INLA and Extensions

Facilitates spatial and general latent Gaussian modeling using integrated nested Laplace approximation via the INLA package (<https://www.r-inla.org>). Additionally, extends the GAM-like model class to more general nonlinear predictor expressions, and implements a log Gaussian Cox process likelihood for modeling univariate and spatial point processes based on ecological survey data. Model components are specified with general inputs and mapping methods to the latent variables, and the predictors are specified via general R expressions, with separate expressions for each observation likelihood model in multi-likelihood models. A prediction method based on fast Monte Carlo sampling allows posterior prediction of general expressions of the latent variables. Ecology-focused introduction in Bachl, Lindgren, Borchers, and Illian (2019) <doi:10.1111/2041-210X.13168>.

Maintained by Finn Lindgren. Last updated 8 hours ago.

97 stars 12.59 score 832 scripts 6 dependents

massimoaria

bibliometrix:Comprehensive Science Mapping Analysis

Tool for quantitative research in scientometrics and bibliometrics. It implements the comprehensive workflow for science mapping analysis proposed in Aria M. and Cuccurullo C. (2017) <doi:10.1016/j.joi.2017.08.007>. 'bibliometrix' provides various routines for importing bibliographic data from 'SCOPUS', 'Clarivate Analytics Web of Science' (<https://www.webofknowledge.com/>), 'Digital Science Dimensions' (<https://www.dimensions.ai/>), 'OpenAlex' (<https://openalex.org/>), 'Cochrane Library' (<https://www.cochranelibrary.com/>), 'Lens' (<https://lens.org>), and 'PubMed' (<https://pubmed.ncbi.nlm.nih.gov/>) databases, performing bibliometric analysis and building networks for co-citation, coupling, scientific collaboration and co-word analysis.

Maintained by Massimo Aria. Last updated 15 days ago.

bibliometric-analysis bibliometrics citation citation-network citations co-authors co-occurence co-word-analysis correspondence-analysis coupling isi-web journal manuscript quantitative-analysis scholars science science-mapping scientific scientometrics scopus

545 stars 12.54 score 518 scripts 2 dependents

bioc

microbiome:Microbiome Analytics

Utilities for microbiome analysis.

Maintained by Leo Lahti. Last updated 5 months ago.

metagenomics microbiome sequencing systemsbiology hitchip hitchip-atlas human-microbiome microbiology microbiome-analysis phyloseq population-study

293 stars 12.51 score 2.0k scripts 5 dependents

asardaes

dtwclust:Time Series Clustering Along with Optimizations for the Dynamic Time Warping Distance

Time series clustering along with optimized techniques related to the Dynamic Time Warping distance and its corresponding lower bounds. Implementations of partitional, hierarchical, fuzzy, k-Shape and TADPole clustering are available. Functionality can be easily extended with custom distance measures and centroid definitions. Implementations of DTW barycenter averaging, a distance based on global alignment kernels, and the soft-DTW distance and centroid routines are also provided. All included distance functions have custom loops optimized for the calculation of cross-distance matrices, including parallelization support. Several cluster validity indices are included.

Maintained by Alexis Sarda. Last updated 8 months ago.

clustering dtw time-series openblas cpp

262 stars 12.35 score 406 scripts 14 dependents

eliocamp

metR:Tools for Easier Analysis of Meteorological Fields

Many useful functions and extensions for dealing with meteorological data in the tidy data framework. Extends 'ggplot2' for better plotting of scalar and vector fields and provides commonly used analysis methods in the atmospheric sciences.

Maintained by Elio Campitelli. Last updated 14 days ago.

atmospheric-science ggplot2 visualization

146 stars 12.30 score 1000 scripts 22 dependents

bioc

ReactomePA:Reactome Pathway Analysis

This package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization. This package is not affiliated with the Reactome team.

Maintained by Guangchuang Yu. Last updated 5 months ago.

pathways visualization annotation multiplecomparison genesetenrichment reactome enrichment-analysis reactome-pathway-analysis reactomepa

40 stars 12.25 score 1.5k scripts 7 dependents

bioc

ggbio:Visualization tools for genomic data

The ggbio package extends and specializes the grammar of graphics for biological data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries.

Maintained by Michael Lawrence. Last updated 5 months ago.

infrastructure visualization

111 stars 12.23 score 734 scripts 16 dependents

topepo

C50:C5.0 Decision Trees and Rule-Based Models

C5.0 decision trees and rule-based models for pattern recognition that extend the work of Quinlan (1993, ISBN:1-55860-238-0).

Maintained by Max Kuhn. Last updated 7 days ago.

53 stars 12.09 score 1.3k scripts 13 dependents

bcallaway11

did:Treatment Effects with Multiple Periods and Groups

The standard Difference-in-Differences (DID) setup involves two periods and two groups -- a treated group and untreated group. Many applications of DID methods involve more than two periods and have individuals that are treated at different points in time. This package contains tools for computing average treatment effect parameters in Difference in Differences setups with more than two periods and with variation in treatment timing using the methods developed in Callaway and Sant'Anna (2021) <doi:10.1016/j.jeconom.2020.12.001>. The main parameters are group-time average treatment effects which are the average treatment effect for a particular group at a a particular time. These can be aggregated into a fewer number of treatment effect parameters, and the package deals with the cases where there is selective treatment timing, dynamic treatment effects, calendar time effects, or combinations of these. There are also functions for testing the Difference in Differences assumption, and plotting group-time average treatment effects.

Maintained by Brantly Callaway. Last updated 7 days ago.

329 stars 12.09 score 696 scripts 3 dependents

mrc-ide

EpiEstim:Estimate Time Varying Reproduction Numbers from Epidemic Curves

Tools to quantify transmissibility throughout an epidemic from the analysis of time series of incidence as described in Cori et al. (2013) <doi:10.1093/aje/kwt133> and Wallinga and Teunis (2004) <doi:10.1093/aje/kwh255>.

Maintained by Anne Cori. Last updated 7 months ago.

95 stars 12.06 score 1.0k scripts 7 dependents

ropensci

RefManageR:Straightforward 'BibTeX' and 'BibLaTeX' Bibliography Management

Provides tools for importing and working with bibliographic references. It greatly enhances the 'bibentry' class by providing a class 'BibEntry' which stores 'BibTeX' and 'BibLaTeX' references, supports 'UTF-8' encoding, and can be easily searched by any field, by date ranges, and by various formats for name lists (author by last names, translator by full names, etc.). Entries can be updated, combined, sorted, printed in a number of styles, and exported. 'BibTeX' and 'BibLaTeX' '.bib' files can be read into 'R' and converted to 'BibEntry' objects. Interfaces to 'NCBI Entrez', 'CrossRef', and 'Zotero' are provided for importing references and references can be created from locally stored 'PDF' files using 'Poppler'. Includes functions for citing and generating a bibliography with hyperlinks for documents prepared with 'RMarkdown' or 'RHTML'.

Maintained by Mathew W. McLean. Last updated 5 months ago.

peer-reviewed

115 stars 12.06 score 2.3k scripts 16 dependents

zachmayer

caretEnsemble:Ensembles of Caret Models

Functions for creating ensembles of caret models: caretList() and caretStack(). caretList() is a convenience function for fitting multiple caret::train() models to the same dataset. caretStack() will make linear or non-linear combinations of these models, using a caret::train() model as a meta-model.

Maintained by Zachary A. Deane-Mayer. Last updated 4 months ago.

226 stars 11.98 score 780 scripts 1 dependents

stefanedwards

lemon:Freshing Up your 'ggplot2' Plots

Functions for working with legends and axis lines of 'ggplot2', facets that repeat axis lines on all panels, and some 'knitr' extensions.

Maintained by Stefan McKinnon Edwards. Last updated 5 months ago.

axis-lines facets ggplot-extension ggplot2 knitr legend ticks visualization

190 stars 11.98 score 1.7k scripts 4 dependents

xfim

ggmcmc:Tools for Analyzing MCMC Simulations from Bayesian Inference

Tools for assessing and diagnosing convergence of Markov Chain Monte Carlo simulations, as well as for graphically display results from full MCMC analysis. The package also facilitates the graphical interpretation of models by providing flexible functions to plot the results against observed variables, and functions to work with hierarchical/multilevel batches of parameters (Fernández-i-Marín, 2016 <doi:10.18637/jss.v070.i09>).

Maintained by Xavier Fernández i Marín. Last updated 2 years ago.

bayesian-data-analysis ggplot2 graphical jags mcmc stan

111 stars 11.94 score 1.6k scripts 8 dependents

bioc

QFeatures:Quantitative features for mass spectrometry data

The QFeatures infrastructure enables the management and processing of quantitative features for high-throughput mass spectrometry assays. It provides a familiar Bioconductor user experience to manages quantitative data across different assay levels (such as peptide spectrum matches, peptides and proteins) in a coherent and tractable format.

Maintained by Laurent Gatto. Last updated 2 days ago.

infrastructure massspectrometry proteomics metabolomics bioconductor mass-spectrometry

27 stars 11.88 score 278 scripts 49 dependents

hannameyer

CAST:'caret' Applications for Spatial-Temporal Models

Supporting functionality to run 'caret' with spatial or spatial-temporal data. 'caret' is a frequently used package for model training and prediction using machine learning. CAST includes functions to improve spatial or spatial-temporal modelling tasks using 'caret'. It includes the newly suggested 'Nearest neighbor distance matching' cross-validation to estimate the performance of spatial prediction models and allows for spatial variable selection to selects suitable predictor variables in view to their contribution to the spatial model performance. CAST further includes functionality to estimate the (spatial) area of applicability of prediction models. Methods are described in Meyer et al. (2018) <doi:10.1016/j.envsoft.2017.12.001>; Meyer et al. (2019) <doi:10.1016/j.ecolmodel.2019.108815>; Meyer and Pebesma (2021) <doi:10.1111/2041-210X.13650>; Milà et al. (2022) <doi:10.1111/2041-210X.13851>; Meyer and Pebesma (2022) <doi:10.1038/s41467-022-29838-9>; Linnenbrink et al. (2023) <doi:10.5194/egusphere-2023-1308>; Schumacher et al. (2024) <doi:10.5194/egusphere-2024-2730>. The package is described in detail in Meyer et al. (2024) <doi:10.48550/arXiv.2404.06978>.

Maintained by Hanna Meyer. Last updated 2 months ago.

autocorrelation caret feature-selection machine-learning overfitting predictive-modeling spatial spatio-temporal variable-selection

114 stars 11.85 score 298 scripts 1 dependents

bioc

methylKit:DNA methylation analysis from high-throughput bisulfite sequencing results

methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods and whole genome bisulfite sequencing. It also has functions to analyze base-pair resolution 5hmC data from experimental protocols such as oxBS-Seq and TAB-Seq. Methylation calling can be performed directly from Bismark aligned BAM files.

Maintained by Altuna Akalin. Last updated 1 months ago.

dnamethylation sequencing methylseq genome-biology methylation statistical-analysis visualization curl bzip2 xz-utils zlib cpp

224 stars 11.78 score 578 scripts 3 dependents

jbryer

likert:Analysis and Visualization Likert Items

An approach to analyzing Likert response items, with an emphasis on visualizations. The stacked bar plot is the preferred method for presenting Likert results. Tabular results are also implemented along with density plots to assist researchers in determining whether Likert responses can be used quantitatively instead of qualitatively. See the likert(), summary.likert(), and plot.likert() functions to get started.

Maintained by Jason Bryer. Last updated 8 days ago.

data-science visualization

310 stars 11.71 score 480 scripts 2 dependents

bioc

variancePartition:Quantify and interpret drivers of variation in multilevel gene expression experiments

Quantify and interpret multiple sources of biological and technical variation in gene expression experiments. Uses a linear mixed model to quantify variation in gene expression attributable to individual, tissue, time point, or technical variables. Includes dream differential expression analysis for repeated measures.

Maintained by Gabriel E. Hoffman. Last updated 3 months ago.

rnaseq geneexpression genesetenrichment differentialexpression batcheffect qualitycontrol regression epigenetics functionalgenomics transcriptomics normalization preprocessing microarray immunooncology software

7 stars 11.69 score 1.1k scripts 3 dependents

haleyjeppson

ggmosaic:Mosaic Plots in the 'ggplot2' Framework

Mosaic plots in the 'ggplot2' framework. Mosaic plot functionality is provided in a single 'ggplot2' layer by calling the geom 'mosaic'.

Maintained by Haley Jeppson. Last updated 6 months ago.

167 stars 11.63 score 1.8k scripts 4 dependents

pecanproject

PEcAn.data.atmosphere:PEcAn Functions Used for Managing Climate Driver Data

The Predictive Ecosystem Carbon Analyzer (PEcAn) is a scientific workflow management tool that is designed to simplify the management of model parameterization, execution, and analysis. The PECAn.data.atmosphere package converts climate driver data into a standard format for models integrated into PEcAn. As a standalone package, it provides an interface to access diverse climate data sets.

Maintained by David LeBauer. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants

216 stars 11.62 score 64 scripts 14 dependents

bioc

mia:Microbiome analysis

mia implements tools for microbiome analysis based on the SummarizedExperiment, SingleCellExperiment and TreeSummarizedExperiment infrastructure. Data wrangling and analysis in the context of taxonomic data is the main scope. Additional functions for common task are implemented such as community indices calculation and summarization.

Maintained by Tuomas Borman. Last updated 2 days ago.

microbiome software dataimport analysis bioconductor cpp

51 stars 11.52 score 316 scripts 5 dependents

sachaepskamp

qgraph:Graph Plotting Methods, Psychometric Data Visualization and Graphical Model Estimation

Fork of qgraph - Weighted network visualization and analysis, as well as Gaussian graphical model computation. See Epskamp et al. (2012) <doi:10.18637/jss.v048.i04>.

Maintained by Sacha Epskamp. Last updated 1 years ago.

cpp

69 stars 11.43 score 1.2k scripts 63 dependents

ewenharrison

finalfit:Quickly Create Elegant Regression Results Tables and Plots when Modelling

Generate regression results tables and plots in final format for publication. Explore models and export directly to PDF and 'Word' using 'RMarkdown'.

Maintained by Ewen Harrison. Last updated 12 days ago.

270 stars 11.43 score 1.0k scripts

bioc

decontam:Identify Contaminants in Marker-gene and Metagenomics Sequencing Data

Simple statistical identification of contaminating sequence features in marker-gene or metagenomics data. Works on any kind of feature derived from environmental sequencing data (e.g. ASVs, OTUs, taxonomic groups, MAGs,...). Requires DNA quantitation data or sequenced negative control samples.

Maintained by Benjamin Callahan. Last updated 5 months ago.

immunooncology microbiome sequencing classification metagenomics amplicon bioinformatics contamination metabarcoding

153 stars 11.42 score 524 scripts 6 dependents

bioc

biomformat:An interface package for the BIOM file format

This is an R package for interfacing with the BIOM format. This package includes basic tools for reading biom-format files, accessing and subsetting data tables from a biom object (which is more complex than a single table), as well as limited support for writing a biom-object back to a biom-format file. The design of this API is intended to match the python API and other tools included with the biom-format project, but with a decidedly "R flavor" that should be familiar to R users. This includes S4 classes and methods, as well as extensions of common core functions/methods.

Maintained by Paul J. McMurdie. Last updated 5 months ago.

immunooncology dataimport metagenomics microbiome

7 stars 11.39 score 416 scripts 40 dependents

bioc

PharmacoGx:Analysis of Large-Scale Pharmacogenomic Data

Contains a set of functions to perform large-scale analysis of pharmaco-genomic data. These include the PharmacoSet object for storing the results of pharmacogenomic experiments, as well as a number of functions for computing common summaries of drug-dose response and correlating them with the molecular features in a cancer cell-line.

Maintained by Benjamin Haibe-Kains. Last updated 3 months ago.

geneexpression pharmacogenetics pharmacogenomics software classification datasets pharmacogenomic pharmacogx cpp

68 stars 11.39 score 442 scripts 3 dependents

bioc

MAST:Model-based Analysis of Single Cell Transcriptomics

Methods and models for handling zero-inflated single cell assay data.

Maintained by Andrew McDavid. Last updated 5 months ago.

geneexpression differentialexpression genesetenrichment rnaseq transcriptomics singlecell

232 stars 11.28 score 1.8k scripts 5 dependents

mrcieu

TwoSampleMR:Two Sample MR Functions and Interface to MRC Integrative Epidemiology Unit OpenGWAS Database

A package for performing Mendelian randomization using GWAS summary data. It uses the IEU OpenGWAS database <https://gwas.mrcieu.ac.uk/> to automatically obtain data, and a wide range of methods to run the analysis.

Maintained by Gibran Hemani. Last updated 6 days ago.

476 stars 11.27 score 1.7k scripts 1 dependents

bioc

ggcyto:Visualize Cytometry data with ggplot

With the dedicated fortify method implemented for flowSet, ncdfFlowSet and GatingSet classes, both raw and gated flow cytometry data can be plotted directly with ggplot. ggcyto wrapper and some customed layers also make it easy to add gates and population statistics to the plot.

Maintained by Mike Jiang. Last updated 5 months ago.

immunooncology flowcytometry cellbasedassays infrastructure visualization

58 stars 11.25 score 362 scripts 5 dependents

adeverse

adespatial:Multivariate Multiscale Spatial Analysis

Tools for the multiscale spatial analysis of multivariate data. Several methods are based on the use of a spatial weighting matrix and its eigenvector decomposition (Moran's Eigenvectors Maps, MEM). Several approaches are described in the review Dray et al (2012) <doi:10.1890/11-1183.1>.

Maintained by Aurélie Siberchicot. Last updated 3 days ago.

fortran openblas

36 stars 11.25 score 398 scripts 2 dependents

boxuancui

DataExplorer:Automate Data Exploration and Treatment

Automated data exploration process for analytic tasks and predictive modeling, so that users could focus on understanding data and extracting insights. The package scans and analyzes each variable, and visualizes them with typical graphical techniques. Common data processing methods are also available to treat and format data.

Maintained by Boxuan Cui. Last updated 1 years ago.

data-analysis data-exploration data-science eda visualization

523 stars 11.21 score 2.2k scripts

jamiemkass

ENMeval:Automated Tuning and Evaluations of Ecological Niche Models

Runs ecological niche models over all combinations of user-defined settings (i.e., tuning), performs cross validation to evaluate models, and returns data tables to aid in selection of optimal model settings that balance goodness-of-fit and model complexity. Also has functions to partition data spatially (or not) for cross validation, to plot multiple visualizations of results, to run null models to estimate significance and effect sizes of performance metrics, and to calculate range overlap between model predictions, among others. The package was originally built for Maxent models (Phillips et al. 2006, Phillips et al. 2017), but the current version allows possible extensions for any modeling algorithm. The extensive vignette, which guides users through most package functionality but unfortunately has a file size too big for CRAN, can be found here on the package's Github Pages website: <https://jamiemkass.github.io/ENMeval/articles/ENMeval-2.0-vignette.html>.

Maintained by Jamie M. Kass. Last updated 5 days ago.

49 stars 11.16 score 332 scripts 2 dependents

bioc

genomation:Summary, annotation and visualization of genomic data

A package for summary and annotation of genomic intervals. Users can visualize and quantify genomic intervals over pre-defined functional regions, such as promoters, exons, introns, etc. The genomic intervals represent regions with a defined chromosome position, which may be associated with a score, such as aligned reads from HT-seq experiments, TF binding sites, methylation scores, etc. The package can use any tabular genomic feature data as long as it has minimal information on the locations of genomic intervals. In addition, It can use BAM or BigWig files as input.

Maintained by Altuna Akalin. Last updated 5 months ago.

annotation sequencing visualization cpgisland cpp

76 stars 11.13 score 738 scripts 5 dependents

bioc

PCAtools:PCAtools: Everything Principal Components Analysis

Principal Component Analysis (PCA) is a very powerful technique that has wide applicability in data science, bioinformatics, and further afield. It was initially developed to analyse large volumes of data in order to tease out the differences/relationships between the logical entities being analysed. It extracts the fundamental structure of the data without the need to build any model to represent it. This 'summary' of the data is arrived at through a process of reduction that can transform the large number of variables into a lesser number that are uncorrelated (i.e. the 'principal components'), while at the same time being capable of easy interpretation on the original data. PCAtools provides functions for data exploration via PCA, and allows the user to generate publication-ready figures. PCA is performed via BiocSingular - users can also identify optimal number of principal components via different metrics, such as elbow method and Horn's parallel analysis, which has relevance for data reduction in single-cell RNA-seq (scRNA-seq) and high dimensional mass cytometry data.

Maintained by Kevin Blighe. Last updated 5 months ago.

rnaseq atacseq geneexpression transcription singlecell principalcomponent cpp

348 stars 11.12 score 832 scripts 2 dependents

juliasilge

widyr:Widen, Process, then Re-Tidy Data

Encapsulates the pattern of untidying data into a wide matrix, performing some processing, then turning it back into a tidy form. This is useful for several operations such as co-occurrence counts, correlations, or clustering that are mathematically convenient on wide matrices.

Maintained by Julia Silge. Last updated 2 years ago.

329 stars 11.12 score 1.7k scripts 2 dependents

fmichonneau

phylobase:Base Package for Phylogenetic Structures and Comparative Data

Provides a base S4 class for comparative methods, incorporating one or more trees and trait data.

Maintained by Francois Michonneau. Last updated 1 years ago.

phylogenetics cpp

18 stars 11.10 score 394 scripts 18 dependents

ropengov

eurostat:Tools for Eurostat Open Data

Tools to download data from the Eurostat database <https://ec.europa.eu/eurostat> together with search and manipulation utilities.

Maintained by Leo Lahti. Last updated 2 months ago.

ropengov eurostat eurostat-data

242 stars 11.07 score 892 scripts 4 dependents

jgx65

hierfstat:Estimation and Tests of Hierarchical F-Statistics

Estimates hierarchical F-statistics from haploid or diploid genetic data with any numbers of levels in the hierarchy, following the algorithm of Yang (Evolution(1998), 52:950). Tests via randomisations the significance of each F and variance components, using the likelihood-ratio statistics G (Goudet et al. (1996) <https://academic.oup.com/genetics/article/144/4/1933/6017091>). Estimates genetic diversity statistics for haploid and diploid genetic datasets in various formats, including inbreeding and coancestry coefficients, and population specific F-statistics following Weir and Goudet (2017) <https://academic.oup.com/genetics/article/206/4/2085/6072590>.

Maintained by Jerome Goudet. Last updated 4 months ago.

devtools fstatistics gwas hierfstat kinship population-genetics population-genomics quantitative-genetics simulations

25 stars 11.06 score 560 scripts 5 dependents

stephenslab

mashr:Multivariate Adaptive Shrinkage

Implements the multivariate adaptive shrinkage (mash) method of Urbut et al (2019) <DOI:10.1038/s41588-018-0268-8> for estimating and testing large numbers of effects in many conditions (or many outcomes). Mash takes an empirical Bayes approach to testing and effect estimation; it estimates patterns of similarity among conditions, then exploits these patterns to improve accuracy of the effect estimates. The core linear algebra is implemented in C++ for fast model fitting and posterior computation.

Maintained by Peter Carbonetto. Last updated 5 months ago.

openblas gsl cpp openmp

91 stars 11.04 score 624 scripts 3 dependents

bioc

Maaslin2:"Multivariable Association Discovery in Population-scale Meta-omics Studies"

MaAsLin2 is comprehensive R package for efficiently determining multivariable association between clinical metadata and microbial meta'omic features. MaAsLin2 relies on general linear models to accommodate most modern epidemiological study designs, including cross-sectional and longitudinal, and offers a variety of data exploration, normalization, and transformation methods. MaAsLin2 is the next generation of MaAsLin.

Maintained by Lauren McIver. Last updated 5 months ago.

metagenomics software microbiome normalization biobakery bioconductor differential-abundance-analysis false-discovery-rate multiple-covariates public repeated-measures tools

133 stars 11.03 score 532 scripts 3 dependents

bioc

CATALYST:Cytometry dATa anALYSis Tools

CATALYST provides tools for preprocessing of and differential discovery in cytometry data such as FACS, CyTOF, and IMC. Preprocessing includes i) normalization using bead standards, ii) single-cell deconvolution, and iii) bead-based compensation. For differential discovery, the package provides a number of convenient functions for data processing (e.g., clustering, dimension reduction), as well as a suite of visualizations for exploratory data analysis and exploration of results from differential abundance (DA) and state (DS) analysis in order to identify differences in composition and expression profiles at the subpopulation-level, respectively.

Maintained by Helena L. Crowell. Last updated 4 months ago.

clustering dataimport differentialexpression experimentaldesign flowcytometry immunooncology massspectrometry normalization preprocessing singlecell software statisticalmethod visualization

67 stars 10.99 score 362 scripts 2 dependents

pecanproject

PEcAn.visualization:PEcAn visualization functions

The Predictive Ecosystem Carbon Analyzer (PEcAn) is a scientific workflow management tool that is designed to simplify the management of model parameterization, execution, and analysis. The goal of PECAn is to streamline the interaction between data and models, and to improve the efficacy of scientific investigation. This module is used to create more complex visualizations from the data generated by PEcAn code, specifically the models.

Maintained by David LeBauer. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants

216 stars 10.97 score 74 scripts 11 dependents

lionel-

ggstance:Horizontal 'ggplot2' Components

A 'ggplot2' extension that provides flipped components: horizontal versions of 'Stats' and 'Geoms', and vertical versions of 'Positions'. This package is now superseded by 'ggplot2' itself which now has full native support for horizontal layouts. It remains available for backward compatibility.

Maintained by Lionel Henry. Last updated 11 months ago.

201 stars 10.95 score 1.0k scripts 5 dependents

sachsmc

plotROC:Generate Useful ROC Curve Charts for Print and Interactive Use

Most ROC curve plots obscure the cutoff values and inhibit interpretation and comparison of multiple curves. This attempts to address those shortcomings by providing plotting and interactive tools. Functions are provided to generate an interactive ROC curve plot for web use, and print versions. A Shiny application implementing the functions is also included.

Maintained by Michael C. Sachs. Last updated 5 months ago.

87 stars 10.93 score 932 scripts 7 dependents

ropensci

CoordinateCleaner:Automated Cleaning of Occurrence Records from Biological Collections

Automated flagging of common spatial and temporal errors in biological and paleontological collection data, for the use in conservation, ecology and paleontology. Includes automated tests to easily flag (and exclude) records assigned to country or province centroid, the open ocean, the headquarters of the Global Biodiversity Information Facility, urban areas or the location of biodiversity institutions (museums, zoos, botanical gardens, universities). Furthermore identifies per species outlier coordinates, zero coordinates, identical latitude/longitude and invalid coordinates. Also implements an algorithm to identify data sets with a significant proportion of rounded coordinates. Especially suited for large data sets. The reference for the methodology is: Zizka et al. (2019) <doi:10.1111/2041-210X.13152>.

Maintained by Alexander Zizka. Last updated 1 years ago.

82 stars 10.93 score 306 scripts 3 dependents

bioc

infercnv:Infer Copy Number Variation from Single-Cell RNA-Seq Data

Using single-cell RNA-Seq expression to visualize CNV in cells.

Maintained by Christophe Georgescu. Last updated 5 months ago.

software copynumbervariation variantdetection structuralvariation genomicvariation genetics transcriptomics statisticalmethod bayesian hiddenmarkovmodel singlecell jags cpp

601 stars 10.92 score 674 scripts

indrajeetpatil

statsExpressions:Tidy Dataframes and Expressions with Statistical Details

Utilities for producing dataframes with rich details for the most common types of statistical approaches and tests: parametric, nonparametric, robust, and Bayesian t-test, one-way ANOVA, correlation analyses, contingency table analyses, and meta-analyses. The functions are pipe-friendly and provide a consistent syntax to work with tidy data. These dataframes additionally contain expressions with statistical details, and can be used in graphing packages. This package also forms the statistical processing backend for 'ggstatsplot'. References: Patil (2021) <doi:10.21105/joss.03236>.

Maintained by Indrajeet Patil. Last updated 1 months ago.

bayesian-inference bayesian-statistics contingency-table correlation effectsize meta-analysis parametric robust robust-statistics statistical-details statistical-tests tidy

312 stars 10.92 score 146 scripts 2 dependents

ohdsi

PatientLevelPrediction:Develop Clinical Prediction Models Using the Common Data Model

A user friendly way to create patient level prediction models using the Observational Medical Outcomes Partnership Common Data Model. Given a cohort of interest and an outcome of interest, the package can use data in the Common Data Model to build a large set of features. These features can then be used to fit a predictive model with a number of machine learning algorithms. This is further described in Reps (2017) <doi:10.1093/jamia/ocy032>.

Maintained by Egill Fridgeirsson. Last updated 26 days ago.

hades openjdk

190 stars 10.85 score 297 scripts

ecmerkle

blavaan:Bayesian Latent Variable Analysis

Fit a variety of Bayesian latent variable models, including confirmatory factor analysis, structural equation models, and latent growth curve models. References: Merkle & Rosseel (2018) <doi:10.18637/jss.v085.i04>; Merkle et al. (2021) <doi:10.18637/jss.v100.i06>.

Maintained by Edgar Merkle. Last updated 15 days ago.

bayesian-statistics factor-analysis growth-curve-models latent-variables missing-data multilevel-models multivariate-analysis path-analysis psychometrics statistical-modeling structural-equation-modeling cpp

92 stars 10.84 score 183 scripts 3 dependents

grunwaldlab

poppr:Genetic Analysis of Populations with Mixed Reproduction

Population genetic analyses for hierarchical analysis of partially clonal populations built upon the architecture of the 'adegenet' package. Originally described in Kamvar, Tabima, and Grünwald (2014) <doi:10.7717/peerj.281> with version 2.0 described in Kamvar, Brooks, and Grünwald (2015) <doi:10.3389/fgene.2015.00208>.

Maintained by Zhian N. Kamvar. Last updated 11 months ago.

clonality genetic-analysis genetic-distances minimum-spanning-networks multilocus-genotypes multilocus-lineages population-genetics populations openmp

69 stars 10.84 score 672 scripts

stephenslab

susieR:Sum of Single Effects Linear Regression

Implements methods for variable selection in linear regression based on the "Sum of Single Effects" (SuSiE) model, as described in Wang et al (2020) <DOI:10.1101/501114> and Zou et al (2021) <DOI:10.1101/2021.11.03.467167>. These methods provide simple summaries, called "Credible Sets", for accurately quantifying uncertainty in which variables should be selected. The methods are motivated by genetic fine-mapping applications, and are particularly well-suited to settings where variables are highly correlated and detectable effects are sparse. The fitting algorithm, a Bayesian analogue of stepwise selection methods called "Iterative Bayesian Stepwise Selection" (IBSS), is simple and fast, allowing the SuSiE model be fit to large data sets (thousands of samples and hundreds of thousands of variables).

Maintained by Peter Carbonetto. Last updated 1 months ago.

203 stars 10.80 score 728 scripts 6 dependents

welch-lab

rliger:Linked Inference of Genomic Experimental Relationships

Uses an extension of nonnegative matrix factorization to identify shared and dataset-specific factors. See Welch J, Kozareva V, et al (2019) <doi:10.1016/j.cell.2019.05.006>, and Liu J, Gao C, Sodicoff J, et al (2020) <doi:10.1038/s41596-020-0391-8> for more details.

Maintained by Yichen Wang. Last updated 3 months ago.

nonnegative-matrix-factorization single-cell openblas cpp

408 stars 10.77 score 334 scripts 1 dependents

bioc

muscat:Multi-sample multi-group scRNA-seq data analysis tools

`muscat` provides various methods and visualization tools for DS analysis in multi-sample, multi-group, multi-(cell-)subpopulation scRNA-seq data, including cell-level mixed models and methods based on aggregated “pseudobulk” data, as well as a flexible simulation platform that mimics both single and multi-sample scRNA-seq data.

Maintained by Helena L. Crowell. Last updated 5 months ago.

immunooncology differentialexpression sequencing singlecell software statisticalmethod visualization

184 stars 10.74 score 686 scripts 1 dependents

pecanproject

PEcAn.benchmark:PEcAn Functions Used for Benchmarking

The Predictive Ecosystem Carbon Analyzer (PEcAn) is a scientific workflow management tool that is designed to simplify the management of model parameterization, execution, and analysis. The goal of PEcAn is to streamline the interaction between data and models, and to improve the efficacy of scientific investigation. The PEcAn.benchmark package provides utilities for comparing models and data, including a suite of statistical metrics and plots.

Maintained by Mike Dietze. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants

216 stars 10.72 score 416 scripts 11 dependents

cjvanlissa

tidySEM:Tidy Structural Equation Modeling

A tidy workflow for generating, estimating, reporting, and plotting structural equation models using 'lavaan', 'OpenMx', or 'Mplus'. Throughout this workflow, elements of syntax, results, and graphs are represented as 'tidy' data, making them easy to customize. Includes functionality to estimate latent class analyses, and to plot 'dagitty' and 'igraph' objects.

Maintained by Caspar J. van Lissa. Last updated 25 days ago.

58 stars 10.69 score 330 scripts 1 dependents

sachaepskamp

semPlot:Path Diagrams and Visual Analysis of Various SEM Packages' Output

Path diagrams and visual analysis of various SEM packages' output.

Maintained by Sacha Epskamp. Last updated 3 years ago.

63 stars 10.64 score 2.1k scripts 13 dependents

hrbrmstr

waffle:Create Waffle Chart Visualizations

Square pie charts (a.k.a. waffle charts) can be used to communicate parts of a whole for categorical quantities. To emulate the percentage view of a pie chart, a 10x10 grid should be used with each square representing 1% of the total. Modern uses of waffle charts do not necessarily adhere to this rule and can be created with a grid of any rectangular shape. Best practices suggest keeping the number of categories small, just as should be done when creating pie charts. Tools are provided to create waffle charts as well as stitch them together, and to use glyphs for making isotype pictograms.

Maintained by Bob Rudis. Last updated 2 years ago.

data-visualisation data-visualization datavisualization ggplot2 square-pie-charts waffle-charts

777 stars 10.62 score 1.3k scripts 5 dependents

bioc

celda:CEllular Latent Dirichlet Allocation

Celda is a suite of Bayesian hierarchical models for clustering single-cell RNA-sequencing (scRNA-seq) data. It is able to perform "bi-clustering" and simultaneously cluster genes into gene modules and cells into cell subpopulations. It also contains DecontX, a novel Bayesian method to computationally estimate and remove RNA contamination in individual cells without empty droplet information. A variety of scRNA-seq data visualization functions is also included.

Maintained by Joshua Campbell. Last updated 2 months ago.

singlecell geneexpression clustering sequencing bayesian immunooncology dataimport cpp openmp

147 stars 10.47 score 256 scripts 2 dependents

petersonr

bestNormalize:Normalizing Transformation Functions

Estimate a suite of normalizing transformations, including a new adaptation of a technique based on ranks which can guarantee normally distributed transformed data if there are no ties: ordered quantile normalization (ORQ). ORQ normalization combines a rank-mapping approach with a shifted logit approximation that allows the transformation to work on data outside the original domain. It is also able to handle new data within the original domain via linear interpolation. The package is built to estimate the best normalizing transformation for a vector consistently and accurately. It implements the Box-Cox transformation, the Yeo-Johnson transformation, three types of Lambert WxF transformations, and the ordered quantile normalization transformation. It estimates the normalization efficacy of other commonly used transformations, and it allows users to specify custom transformations or normalization statistics. Finally, functionality can be integrated into a machine learning workflow via recipes.

Maintained by Ryan Andrew Peterson. Last updated 1 years ago.

39 stars 10.45 score 510 scripts 5 dependents

bioc

scRepertoire:A toolkit for single-cell immune receptor profiling

scRepertoire is a toolkit for processing and analyzing single-cell T-cell receptor (TCR) and immunoglobulin (Ig). The scRepertoire framework supports use of 10x, AIRR, BD, MiXCR, Omniscope, TRUST4, and WAT3R single-cell formats. The functionality includes basic clonal analyses, repertoire summaries, distance-based clustering and interaction with the popular Seurat and SingleCellExperiment/Bioconductor R workflows.

Maintained by Nick Borcherding. Last updated 14 days ago.

software immunooncology singlecell classification annotation sequencing cpp

327 stars 10.42 score 240 scripts

mike-lawrence

ez:Easy Analysis and Visualization of Factorial Experiments

Facilitates easy analysis of factorial experiments, including purely within-Ss designs (a.k.a. "repeated measures"), purely between-Ss designs, and mixed within-and-between-Ss designs. The functions in this package aim to provide simple, intuitive and consistent specification of data analysis and visualization. Visualization functions also include design visualization for pre-analysis data auditing, and correlation matrix visualization. Finally, this package includes functions for non-parametric analysis, including permutation tests and bootstrap resampling. The bootstrap function obtains predictions either by cell means or by more advanced/powerful mixed effects models, yielding predictions and confidence intervals that may be easily visualized at any level of the experiment's design.

Maintained by Michael A. Lawrence. Last updated 8 years ago.

53 stars 10.39 score 2.7k scripts 12 dependents

johnsonhsieh

iNEXT:Interpolation and Extrapolation for Species Diversity

Provides simple functions to compute and plot two types (sample-size- and coverage-based) rarefaction and extrapolation curves for species diversity (Hill numbers) based on individual-based abundance data or sampling-unit- based incidence data; see Chao and others (2014, Ecological Monographs) for pertinent theory and methodologies, and Hsieh, Ma and Chao (2016, Methods in Ecology and Evolution) for an introduction of the R package.

Maintained by T. C. Hsieh. Last updated 1 years ago.

cpp

59 stars 10.38 score 598 scripts 4 dependents

bioc

GENESIS:GENetic EStimation and Inference in Structured samples (GENESIS): Statistical methods for analyzing genetic data from samples with population structure and/or relatedness

The GENESIS package provides methodology for estimating, inferring, and accounting for population and pedigree structure in genetic analyses. The current implementation provides functions to perform PC-AiR (Conomos et al., 2015, Gen Epi) and PC-Relate (Conomos et al., 2016, AJHG). PC-AiR performs a Principal Components Analysis on genome-wide SNP data for the detection of population structure in a sample that may contain known or cryptic relatedness. Unlike standard PCA, PC-AiR accounts for relatedness in the sample to provide accurate ancestry inference that is not confounded by family structure. PC-Relate uses ancestry representative principal components to adjust for population structure/ancestry and accurately estimate measures of recent genetic relatedness such as kinship coefficients, IBD sharing probabilities, and inbreeding coefficients. Additionally, functions are provided to perform efficient variance component estimation and mixed model association testing for both quantitative and binary phenotypes.

Maintained by Stephanie M. Gogarten. Last updated 2 months ago.

snp geneticvariability genetics statisticalmethod dimensionreduction principalcomponent genomewideassociation qualitycontrol biocviews

37 stars 10.36 score 342 scripts 1 dependents

hmsc-r

Hmsc:Hierarchical Model of Species Communities

Hierarchical Modelling of Species Communities (HMSC) is a model-based approach for analyzing community ecological data. This package implements it in the Bayesian framework with Gibbs Markov chain Monte Carlo (MCMC) sampling (Tikhonov et al. (2020) <doi:10.1111/2041-210X.13345>).

Maintained by Otso Ovaskainen. Last updated 14 days ago.

105 stars 10.36 score 476 scripts

bcgov

ssdtools:Species Sensitivity Distributions

Species sensitivity distributions are cumulative probability distributions which are fitted to toxicity concentrations for different species as described by Posthuma et al.(2001) <isbn:9781566705783>. The ssdtools package uses Maximum Likelihood to fit distributions such as the gamma, log-logistic, log-normal and log-normal log-normal mixture. Multiple distributions can be averaged using Akaike Information Criteria. Confidence intervals on hazard concentrations and proportions are produced by bootstrapping.

Maintained by Joe Thorley. Last updated 1 months ago.

ecotoxicology env species-sensitivity-distribution cpp

33 stars 10.33 score 111 scripts 5 dependents

ludvigolsen

cvms:Cross-Validation for Model Selection

Cross-validate one or multiple regression and classification models and get relevant evaluation metrics in a tidy format. Validate the best model on a test set and compare it to a baseline evaluation. Alternatively, evaluate predictions from an external model. Currently supports regression and classification (binary and multiclass). Described in chp. 5 of Jeyaraman, B. P., Olsen, L. R., & Wambugu M. (2019, ISBN: 9781838550134).

Maintained by Ludvig Renbo Olsen. Last updated 27 days ago.

39 stars 10.31 score 492 scripts 5 dependents

bioc

pRoloc:A unifying bioinformatics framework for spatial proteomics

The pRoloc package implements machine learning and visualisation methods for the analysis and interogation of quantitiative mass spectrometry data to reliably infer protein sub-cellular localisation.

Maintained by Lisa Breckels. Last updated 7 days ago.

immunooncology proteomics massspectrometry classification clustering qualitycontrol bioconductor proteomics-data spatial-proteomics visualisation openblas cpp

15 stars 10.31 score 101 scripts 2 dependents

richardli

SUMMER:Small-Area-Estimation Unit/Area Models and Methods for Estimation in R

Provides methods for spatial and spatio-temporal smoothing of demographic and health indicators using survey data, with particular focus on estimating and projecting under-five mortality rates, described in Mercer et al. (2015) <doi:10.1214/15-AOAS872>, Li et al. (2019) <doi:10.1371/journal.pone.0210645>, Wu et al. (DHS Spatial Analysis Reports No. 21, 2021), and Li et al. (2023) <doi:10.48550/arXiv.2007.05117>.

Maintained by Zehang R Li. Last updated 3 months ago.

bayesian-inference small-area-estimation space-time

23 stars 10.28 score 134 scripts 2 dependents

bioc

CAMERA:Collection of annotation related methods for mass spectrometry data

Annotation of peaklists generated by xcms, rule based annotation of isotopes and adducts, isotope validation, EIC correlation based tagging of unknown adducts and fragments

Maintained by Steffen Neumann. Last updated 5 months ago.

immunooncology massspectrometry metabolomics

11 stars 10.27 score 175 scripts 6 dependents

facebookexperimental

Robyn:Semi-Automated Marketing Mix Modeling (MMM) from Meta Marketing Science

Semi-Automated Marketing Mix Modeling (MMM) aiming to reduce human bias by means of ridge regression and evolutionary algorithms, enables actionable decision making providing a budget allocation and diminishing returns curves and allows ground-truth calibration to account for causation.

Maintained by Gufeng Zhou. Last updated 15 days ago.

adstocking budget-allocation cost-response-curve econometrics evolutionary-algorithm gradient-based-optimisation hyperparameter-optimization marketing-mix-modeling marketing-mix-modelling marketing-science mmm ridge-regression

1.3k stars 10.27 score 95 scripts

idigbio

ridigbio:Interface to the iDigBio Data API

An interface to iDigBio's search API that allows downloading specimen records. Searches are returned as a data.frame. Other functions such as the metadata end points return lists of information. iDigBio is a US project focused on digitizing and serving museum specimen collections on the web. See <https://www.idigbio.org> for information on iDigBio.

Maintained by Jesse Bennett. Last updated 22 days ago.

16 stars 10.23 score 63 scripts 7 dependents

florianhartig

BayesianTools:General-Purpose MCMC and SMC Samplers and Tools for Bayesian Statistics

General-purpose MCMC and SMC samplers, as well as plots and diagnostic functions for Bayesian statistics, with a particular focus on calibrating complex system models. Implemented samplers include various Metropolis MCMC variants (including adaptive and/or delayed rejection MH), the T-walk, two differential evolution MCMCs, two DREAM MCMCs, and a sequential Monte Carlo (SMC) particle filter.

Maintained by Florian Hartig. Last updated 1 years ago.

bayes ecological-models mcmc optimization smc systems-biology cpp

124 stars 10.18 score 580 scripts 5 dependents

bioc

singleCellTK:Comprehensive and Interactive Analysis of Single Cell RNA-Seq Data

The Single Cell Toolkit (SCTK) in the singleCellTK package provides an interface to popular tools for importing, quality control, analysis, and visualization of single cell RNA-seq data. SCTK allows users to seamlessly integrate tools from various packages at different stages of the analysis workflow. A general "a la carte" workflow gives users the ability access to multiple methods for data importing, calculation of general QC metrics, doublet detection, ambient RNA estimation and removal, filtering, normalization, batch correction or integration, dimensionality reduction, 2-D embedding, clustering, marker detection, differential expression, cell type labeling, pathway analysis, and data exporting. Curated workflows can be used to run Seurat and Celda. Streamlined quality control can be performed on the command line using the SCTK-QC pipeline. Users can analyze their data using commands in the R console or by using an interactive Shiny Graphical User Interface (GUI). Specific analyses or entire workflows can be summarized and shared with comprehensive HTML reports generated by Rmarkdown. Additional documentation and vignettes can be found at camplab.net/sctk.

Maintained by Joshua David Campbell. Last updated 1 months ago.

singlecell geneexpression differentialexpression alignment clustering immunooncology batcheffect normalization qualitycontrol dataimport gui

182 stars 10.17 score 252 scripts

ropensci

rcrossref:Client for Various 'CrossRef' 'APIs'

Client for various 'CrossRef' 'APIs', including 'metadata' search with their old and newer search 'APIs', get 'citations' in various formats (including 'bibtex', 'citeproc-json', 'rdf-xml', etc.), convert 'DOIs' to 'PMIDs', and 'vice versa', get citations for 'DOIs', and get links to full text of articles when available.

Maintained by Najko Jahn. Last updated 2 years ago.

text-ming literature pdf xml publications citations full-text tdm crossref api api-wrapper crossref-api doi metadata

171 stars 10.15 score 404 scripts 10 dependents

cboettig

knitcitations:Citations for 'Knitr' Markdown Files

Provides the ability to create dynamic citations in which the bibliographic information is pulled from the web rather than having to be entered into a local database such as 'bibtex' ahead of time. The package is primarily aimed at authoring in the R 'markdown' format, and can provide outputs for web-based authoring such as linked text for inline citations. Cite using a 'DOI', URL, or 'bibtex' file key. See the package URL for details.

Maintained by Carl Boettiger. Last updated 4 years ago.

220 stars 10.14 score 836 scripts 2 dependents

fsolt

dotwhisker:Dot-and-Whisker Plots of Regression Results

Create quick and easy dot-and-whisker plots of regression results. It takes as input either (1) a coefficient table in standard form or (2) one (or a list of) fitted model objects (of any type that has methods implemented in the 'parameters' package). It returns 'ggplot' objects that can be further customized using tools from the 'ggplot2' package. The package also includes helper functions for tasks such as rescaling coefficients or relabeling predictor variables. See more methodological discussion of the visualization and data management methods used in this package in Kastellec and Leoni (2007) <doi:10.1017/S1537592707072209> and Gelman (2008) <doi:10.1002/sim.3107>.

Maintained by Yue Hu. Last updated 6 months ago.

graphics plot regression-models

60 stars 10.14 score 680 scripts

bioc

BASiCS:Bayesian Analysis of Single-Cell Sequencing data

Single-cell mRNA sequencing can uncover novel cell-to-cell heterogeneity in gene expression levels in seemingly homogeneous populations of cells. However, these experiments are prone to high levels of technical noise, creating new challenges for identifying genes that show genuine heterogeneous expression within the population of cells under study. BASiCS (Bayesian Analysis of Single-Cell Sequencing data) is an integrated Bayesian hierarchical model to perform statistical analyses of single-cell RNA sequencing datasets in the context of supervised experiments (where the groups of cells of interest are known a priori, e.g. experimental conditions or cell types). BASiCS performs built-in data normalisation (global scaling) and technical noise quantification (based on spike-in genes). BASiCS provides an intuitive detection criterion for highly (or lowly) variable genes within a single group of cells. Additionally, BASiCS can compare gene expression patterns between two or more pre-specified groups of cells. Unlike traditional differential expression tools, BASiCS quantifies changes in expression that lie beyond comparisons of means, also allowing the study of changes in cell-to-cell heterogeneity. The latter can be quantified via a biological over-dispersion parameter that measures the excess of variability that is observed with respect to Poisson sampling noise, after normalisation and technical noise removal. Due to the strong mean/over-dispersion confounding that is typically observed for scRNA-seq datasets, BASiCS also tests for changes in residual over-dispersion, defined by residual values with respect to a global mean/over-dispersion trend.

Maintained by Catalina Vallejos. Last updated 5 months ago.

immunooncology normalization sequencing rnaseq software geneexpression transcriptomics singlecell differentialexpression bayesian cellbiology bioconductor-package gene-expression rcpp rcpparmadillo scrna-seq single-cell openblas cpp openmp

83 stars 10.14 score 368 scripts 1 dependents

mfasiolo

qgam:Smooth Additive Quantile Regression Models

Smooth additive quantile regression models, fitted using the methods of Fasiolo et al. (2020) <doi:10.1080/01621459.2020.1725521>. See Fasiolo at al. (2021) <doi:10.18637/jss.v100.i09> for an introduction to the package. Differently from 'quantreg', the smoothing parameters are estimated automatically by marginal loss minimization, while the regression coefficients are estimated using either PIRLS or Newton algorithm. The learning rate is determined so that the Bayesian credible intervals of the estimated effects have approximately the correct coverage. The main function is qgam() which is similar to gam() in 'mgcv', but fits non-parametric quantile regression models.

Maintained by Matteo Fasiolo. Last updated 23 days ago.

33 stars 10.13 score 133 scripts 15 dependents

bleutner

RStoolbox:Remote Sensing Data Analysis

Toolbox for remote sensing image processing and analysis such as calculating spectral indexes, principal component transformation, unsupervised and supervised classification or fractional cover analyses.

Maintained by Konstantin Mueller. Last updated 2 months ago.

ggplot2 land-cover-mapping remote-sensing spectral-unmixing supervised-classification unsupervised-classification openblas cpp

275 stars 10.10 score 1.1k scripts

ropensci

spocc:Interface to Species Occurrence Data Sources

A programmatic interface to many species occurrence data sources, including Global Biodiversity Information Facility ('GBIF'), 'iNaturalist', 'eBird', Integrated Digitized 'Biocollections' ('iDigBio'), 'VertNet', Ocean 'Biogeographic' Information System ('OBIS'), and Atlas of Living Australia ('ALA'). Includes functionality for retrieving species occurrence data, and combining those data.

Maintained by Hannah Owens. Last updated 2 months ago.

specimens api web-services occurrences species taxonomy gbif inat vertnet ebird idigbio obis ala antweb bison data ecoengine inaturalist occurrence species-occurrence spocc

118 stars 10.09 score 552 scripts 5 dependents

constantamateur

SoupX:Single Cell mRNA Soup eXterminator

Quantify, profile and remove ambient mRNA contamination (the "soup") from droplet based single cell RNA-seq experiments. Implements the method described in Young et al. (2018) <doi:10.1101/303727>.

Maintained by Matthew Daniel Young. Last updated 2 years ago.

266 stars 10.08 score 594 scripts 1 dependents

chiliubio

microeco:Microbial Community Ecology Data Analysis

A series of statistical and plotting approaches in microbial community ecology based on the R6 class. The classes are designed for data preprocessing, taxa abundance plotting, alpha diversity analysis, beta diversity analysis, differential abundance test, null model analysis, network analysis, machine learning, environmental data analysis and functional analysis.

Maintained by Chi Liu. Last updated 6 days ago.

222 stars 10.07 score 211 scripts 3 dependents

adeverse

adephylo:Exploratory Analyses for the Phylogenetic Comparative Method

Multivariate tools to analyze comparative data, i.e. a phylogeny and some traits measured for each taxa. The package contains functions to represent comparative data, compute phylogenetic proximities, perform multivariate analysis with phylogenetic constraints and test for the presence of phylogenetic autocorrelation. The package is described in Jombart et al (2010) <doi:10.1093/bioinformatics/btq292>.

Maintained by Aurélie Siberchicot. Last updated 20 days ago.

9 stars 10.05 score 312 scripts 4 dependents

mages

ChainLadder:Statistical Methods and Models for Claims Reserving in General Insurance

Various statistical methods and models which are typically used for the estimation of outstanding claims reserves in general insurance, including those to estimate the claims development result as required under Solvency II.

Maintained by Markus Gesmann. Last updated 2 months ago.

82 stars 10.04 score 196 scripts 2 dependents

bioc

MOFA2:Multi-Omics Factor Analysis v2

The MOFA2 package contains a collection of tools for training and analysing multi-omic factor analysis (MOFA). MOFA is a probabilistic factor model that aims to identify principal axes of variation from data sets that can comprise multiple omic layers and/or groups of samples. Additional time or space information on the samples can be incorporated using the MEFISTO framework, which is part of MOFA2. Downstream analysis functions to inspect molecular features underlying each factor, vizualisation, imputation etc are available.

Maintained by Ricard Argelaguet. Last updated 5 months ago.

dimensionreduction bayesian visualization factor-analysis mofa multi-omics

326 stars 10.03 score 502 scripts

bioc

singscore:Rank-based single-sample gene set scoring method

A simple single-sample gene signature scoring method that uses rank-based statistics to analyze the sample's gene expression profile. It scores the expression activities of gene sets at a single-sample level.

Maintained by Malvika Kharbanda. Last updated 5 months ago.

software geneexpression genesetenrichment bioinformatics

41 stars 10.03 score 124 scripts 4 dependents

bioc

derfinder:Annotation-agnostic differential expression analysis of RNA-seq data at base-pair resolution via the DER Finder approach

This package provides functions for annotation-agnostic differential expression analysis of RNA-seq data. Two implementations of the DER Finder approach are included in this package: (1) single base-level F-statistics and (2) DER identification at the expressed regions-level. The DER Finder approach can also be used to identify differentially bounded ChIP-seq peaks.

Maintained by Leonardo Collado-Torres. Last updated 4 months ago.

differentialexpression sequencing rnaseq chipseq differentialpeakcalling software immunooncology coverage annotation-agnostic bioconductor derfinder

42 stars 10.03 score 78 scripts 6 dependents

bioc

diffcyt:Differential discovery in high-dimensional cytometry via high-resolution clustering

Statistical methods for differential discovery analyses in high-dimensional cytometry data (including flow cytometry, mass cytometry or CyTOF, and oligonucleotide-tagged cytometry), based on a combination of high-resolution clustering and empirical Bayes moderated tests adapted from transcriptomics.

Maintained by Lukas M. Weber. Last updated 2 months ago.

immunooncology flowcytometry proteomics singlecell cellbasedassays cellbiology clustering featureextraction software

20 stars 9.98 score 225 scripts 5 dependents

ropensci

RNeXML:Semantically Rich I/O for the 'NeXML' Format

Provides access to phyloinformatic data in 'NeXML' format. The package should add new functionality to R such as the possibility to manipulate 'NeXML' objects in more various and refined way and compatibility with 'ape' objects.

Maintained by Carl Boettiger. Last updated 11 months ago.

metadata nexml phylogenetics linked-data

13 stars 9.97 score 100 scripts 19 dependents

pecanproject

PEcAn.assim.batch:PEcAn Functions Used for Ecological Forecasts and Reanalysis

The Predictive Ecosystem Carbon Analyzer (PEcAn) is a scientific workflow management tool that is designed to simplify the management of model parameterization, execution, and analysis. The goal of PECAn is to streamline the interaction between data and models, and to improve the efficacy of scientific investigation.

Maintained by Istem Fer. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants jags cpp

216 stars 9.96 score 20 scripts 2 dependents

nikita-moor

ldatuning:Tuning of the Latent Dirichlet Allocation Models Parameters

This library estimates the best fitting number of topics.

Maintained by Nathan Chaney. Last updated 10 months ago.

75 stars 9.95 score 356 scripts 5 dependents

tlverse

sl3:Pipelines for Machine Learning and Super Learning

A modern implementation of the Super Learner prediction algorithm, coupled with a general purpose framework for composing arbitrary pipelines for machine learning tasks.

Maintained by Jeremy Coyle. Last updated 5 months ago.

data-science ensemble-learning ensemble-model machine-learning model-selection regression stacking statistics

100 stars 9.94 score 748 scripts 7 dependents

natverse

nat:NeuroAnatomy Toolbox for Analysis of 3D Image Data

NeuroAnatomy Toolbox (nat) enables analysis and visualisation of 3D biological image data, especially traced neurons. Reads and writes 3D images in NRRD and 'Amira' AmiraMesh formats and reads surfaces in 'Amira' hxsurf format. Traced neurons can be imported from and written to SWC and 'Amira' LineSet and SkeletonGraph formats. These data can then be visualised in 3D via 'rgl', manipulated including applying calculated registrations, e.g. using the 'CMTK' registration suite, and analysed. There is also a simple representation for neurons that have been subjected to 3D skeletonisation but not formally traced; this allows morphological comparison between neurons including searches and clustering (via the 'nat.nblast' extension package).

Maintained by Gregory Jefferis. Last updated 6 months ago.

3d connectomics image-analysis neuroanatomy neuroanatomy-toolbox neuron neuron-morphology neuroscience visualisation

67 stars 9.94 score 436 scripts 2 dependents

dataoneorg

dataone:R Interface to the DataONE REST API

Provides read and write access to data and metadata from the DataONE network <https://www.dataone.org> of data repositories. Each DataONE repository implements a consistent repository application programming interface. Users call methods in R to access these remote repository functions, such as methods to query the metadata catalog, get access to metadata for particular data packages, and read the data objects from the data repository. Users can also insert and update data objects on repositories that support these methods.

Maintained by Matthew B. Jones. Last updated 3 years ago.

36 stars 9.93 score 472 scripts 3 dependents

nicholasjclark

mvgam:Multivariate (Dynamic) Generalized Additive Models

Fit Bayesian Dynamic Generalized Additive Models to multivariate observations. Users can build nonlinear State-Space models that can incorporate semiparametric effects in observation and process components, using a wide range of observation families. Estimation is performed using Markov Chain Monte Carlo with Hamiltonian Monte Carlo in the software 'Stan'. References: Clark & Wells (2023) <doi:10.1111/2041-210X.13974>.

Maintained by Nicholas J Clark. Last updated 4 hours ago.

bayesian-statistics dynamic-factor-models ecological-modelling forecasting gaussian-process generalised-additive-models generalized-additive-models joint-species-distribution-modelling multilevel-models multivariate-timeseries stan time-series-analysis timeseries vector-autoregression vectorautoregression cpp

149 stars 9.93 score 117 scripts

laresbernardo

lares:Analytics & Machine Learning Sidekick

Auxiliary package for better/faster analytics, visualization, data mining, and machine learning tasks. With a wide variety of family functions, like Machine Learning, Data Wrangling, Marketing Mix Modeling (Robyn), Exploratory, API, and Scrapper, it helps the analyst or data scientist to get quick and robust results, without the need of repetitive coding or advanced R programming skills.

Maintained by Bernardo Lares. Last updated 1 months ago.

analytics api automation automl data-science descriptive-statistics h2o machine-learning marketing mmm predictive-modeling puzzle rlanguage robyn visualization

233 stars 9.92 score 185 scripts 1 dependents

n8thangreen

BCEA:Bayesian Cost Effectiveness Analysis

Produces an economic evaluation of a sample of suitable variables of cost and effectiveness / utility for two or more interventions, e.g. from a Bayesian model in the form of MCMC simulations. This package computes the most cost-effective alternative and produces graphical summaries and probabilistic sensitivity analysis, see Baio et al (2017) <doi:10.1007/978-3-319-55718-2>.

Maintained by Gianluca Baio. Last updated 2 months ago.

bayesian cost-effectiveness

3 stars 9.90 score 243 scripts 3 dependents

bioc

methylumi:Handle Illumina methylation data

This package provides classes for holding and manipulating Illumina methylation data. Based on eSet, it can contain MIAME information, sample information, feature information, and multiple matrices of data. An "intelligent" import function, methylumiR can read the Illumina text files and create a MethyLumiSet. methylumIDAT can directly read raw IDAT files from HumanMethylation27 and HumanMethylation450 microarrays. Normalization, background correction, and quality control features for GoldenGate, Infinium, and Infinium HD arrays are also included.

Maintained by Sean Davis. Last updated 5 months ago.

dnamethylation twochannel preprocessing qualitycontrol cpgisland

9 stars 9.90 score 89 scripts 9 dependents

environmentalinformatics-marburg

satellite:Handling and Manipulating Remote Sensing Data

Herein, we provide a broad variety of functions which are useful for handling, manipulating, and visualizing satellite-based remote sensing data. These operations range from mere data import and layer handling (eg subsetting), over Raster* typical data wrangling (eg crop, extend), to more sophisticated (pre-)processing tasks typically applied to satellite imagery (eg atmospheric and topographic correction). This functionality is complemented by a full access to the satellite layers' metadata at any stage and the documentation of performed actions in a separate log file. Currently available sensors include Landsat 4-5 (TM), 7 (ETM+), and 8 (OLI/TIRS Combined), and additional compatibility is ensured for the Landsat Global Land Survey data set.

Maintained by Florian Detsch. Last updated 1 years ago.

cpp

22 stars 9.88 score 61 scripts 27 dependents

bioc

GenVisR:Genomic Visualizations in R

Produce highly customizable publication quality graphics for genomic data primarily at the cohort level.

Maintained by Zachary Skidmore. Last updated 5 months ago.

infrastructure datarepresentation classification dnaseq

217 stars 9.87 score 76 scripts

hadley

reshape:Flexibly Reshape Data

Flexibly restructure and aggregate data using just two functions: melt and cast.

Maintained by Hadley Wickham. Last updated 3 years ago.

9.86 score 21k scripts 232 dependents

pitakakariki

simr:Power Analysis for Generalised Linear Mixed Models by Simulation

Calculate power for generalised linear mixed models, using simulation. Designed to work with models fit using the 'lme4' package. Described in Green and MacLeod, 2016 <doi:10.1111/2041-210X.12504>.

Maintained by Peter Green. Last updated 2 years ago.

70 stars 9.82 score 756 scripts

bioc

annotatr:Annotation of Genomic Regions to Genomic Annotations

Given a set of genomic sites/regions (e.g. ChIP-seq peaks, CpGs, differentially methylated CpGs or regions, SNPs, etc.) it is often of interest to investigate the intersecting genomic annotations. Such annotations include those relating to gene models (promoters, 5'UTRs, exons, introns, and 3'UTRs), CpGs (CpG islands, CpG shores, CpG shelves), or regulatory sequences such as enhancers. The annotatr package provides an easy way to summarize and visualize the intersection of genomic sites/regions with genomic annotations.

Maintained by Raymond G. Cavalcante. Last updated 5 months ago.

software annotation genomeannotation functionalgenomics visualization genome-annotation

26 stars 9.76 score 246 scripts 5 dependents

insightsengineering

teal.modules.general:General Modules for 'teal' Applications

Prebuilt 'shiny' modules containing tools for viewing data, visualizing data, understanding missing and outlier values within your data and performing simple data analysis. This extends 'teal' framework that supports reproducible research and analysis.

Maintained by Dawid Kaledkowski. Last updated 2 days ago.

general-purpose modules nest shiny

13 stars 9.74 score 71 scripts

epiforecasts

socialmixr:Social Mixing Matrices for Infectious Disease Modelling

Provides methods for sampling contact matrices from diary data for use in infectious disease modelling, as discussed in Mossong et al. (2008) <doi:10.1371/journal.pmed.0050074>.

Maintained by Sebastian Funk. Last updated 6 months ago.

38 stars 9.74 score 227 scripts 1 dependents

bioc

MicrobiotaProcess:A comprehensive R package for managing and analyzing microbiome and other ecological data within the tidy framework

MicrobiotaProcess is an R package for analysis, visualization and biomarker discovery of microbial datasets. It introduces MPSE class, this make it more interoperable with the existing computing ecosystem. Moreover, it introduces a tidy microbiome data structure paradigm and analysis grammar. It provides a wide variety of microbiome data analysis procedures under the unified and common framework (tidy-like framework).

Maintained by Shuangbin Xu. Last updated 5 months ago.

visualization microbiome software multiplecomparison featureextraction microbiome-analysis microbiome-data

186 stars 9.70 score 126 scripts 1 dependents

pecanproject

PEcAnRTM:PEcAn Functions Used for Radiative Transfer Modeling

Functions for performing forward runs and inversions of radiative transfer models (RTMs). Inversions can be performed using maximum likelihood, or more complex hierarchical Bayesian methods. Underlying numerical analyses are optimized for speed using Fortran code.

Maintained by Alexey Shiklomanov. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants fortran jags cpp

216 stars 9.70 score 132 scripts

fawda123

NeuralNetTools:Visualization and Analysis Tools for Neural Networks

Visualization and analysis tools to aid in the interpretation of neural network models. Functions are available for plotting, quantifying variable importance, conducting a sensitivity analysis, and obtaining a simple list of model weights.

Maintained by Marcus W. Beck. Last updated 3 years ago.

72 stars 9.70 score 530 scripts 6 dependents

bblonder

hypervolume:High Dimensional Geometry, Set Operations, Projection, and Inference Using Kernel Density Estimation, Support Vector Machines, and Convex Hulls

Estimates the shape and volume of high-dimensional datasets and performs set operations: intersection / overlap, union, unique components, inclusion test, and hole detection. Uses stochastic geometry approach to high-dimensional kernel density estimation, support vector machine delineation, and convex hull generation. Applications include modeling trait and niche hypervolumes and species distribution modeling.

Maintained by Benjamin Blonder. Last updated 3 months ago.

openblas cpp

23 stars 9.69 score 211 scripts 7 dependents

muschellij2

rscopus:Scopus Database 'API' Interface

Uses Elsevier 'Scopus' API <https://dev.elsevier.com/sc_apis.html> to download information about authors and their citations.

Maintained by John Muschelli. Last updated 1 days ago.

bibliometrics scopus scopus-api

77 stars 9.67 score 124 scripts 3 dependents

grunwaldlab

metacoder:Tools for Parsing, Manipulating, and Graphing Taxonomic Abundance Data

Reads, plots, and manipulates large taxonomic data sets, like those generated from modern high-throughput sequencing, such as metabarcoding (i.e. amplification metagenomics, 16S metagenomics, etc). It provides a tree-based visualization called "heat trees" used to depict statistics for every taxon in a taxonomy using color and size. It also provides various functions to do common tasks in microbiome bioinformatics on data in the 'taxmap' format defined by the 'taxa' package. The 'metacoder' package is described in the publication by Foster et al. (2017) <doi:10.1371/journal.pcbi.1005404>.

Maintained by Zachary Foster. Last updated 2 months ago.

community-diversity hierarchical metabarcoding pcr taxonomy trees cpp

140 stars 9.64 score 328 scripts

bxc147

Epi:Statistical Analysis in Epidemiology

Functions for demographic and epidemiological analysis in the Lexis diagram, i.e. register and cohort follow-up data. In particular representation, manipulation, rate estimation and simulation for multistate data - the Lexis suite of functions, which includes interfaces to 'mstate', 'etm' and 'cmprsk' packages. Contains functions for Age-Period-Cohort and Lee-Carter modeling and a function for interval censored data and some useful functions for tabulation and plotting, as well as a number of epidemiological data sets.

Maintained by Bendix Carstensen. Last updated 3 months ago.

4 stars 9.64 score 708 scripts 11 dependents

bioc

pcaExplorer:Interactive Visualization of RNA-seq Data Using a Principal Components Approach

This package provides functionality for interactive visualization of RNA-seq datasets based on Principal Components Analysis. The methods provided allow for quick information extraction and effective data exploration. A Shiny application encapsulates the whole analysis.

Maintained by Federico Marini. Last updated 3 months ago.

immunooncology visualization rnaseq dimensionreduction principalcomponent qualitycontrol gui reportwriting shinyapps bioconductor principal-components reproducible-research rna-seq-analysis rna-seq-data shiny transcriptome user-friendly

56 stars 9.63 score 180 scripts

bioc

clusterExperiment:Compare Clusterings for Single-Cell Sequencing

Provides functionality for running and comparing many different clusterings of single-cell sequencing data or other large mRNA Expression data sets.

Maintained by Elizabeth Purdom. Last updated 5 months ago.

clustering rnaseq sequencing software singlecell cpp

38 stars 9.62 score 192 scripts 1 dependents

donaldrwilliams

BGGM:Bayesian Gaussian Graphical Models

Fit Bayesian Gaussian graphical models. The methods are separated into two Bayesian approaches for inference: hypothesis testing and estimation. There are extensions for confirmatory hypothesis testing, comparing Gaussian graphical models, and node wise predictability. These methods were recently introduced in the Gaussian graphical model literature, including Williams (2019) <doi:10.31234/osf.io/x8dpr>, Williams and Mulder (2019) <doi:10.31234/osf.io/ypxd8>, Williams, Rast, Pericchi, and Mulder (2019) <doi:10.31234/osf.io/yt386>.

Maintained by Philippe Rast. Last updated 3 months ago.

bayes-factors bayesian-hypothesis-testing gaussian-graphical-models openblas cpp openmp

55 stars 9.61 score 102 scripts 1 dependents

modeloriented

randomForestExplainer:Explaining and Visualizing Random Forests in Terms of Variable Importance

A set of tools to help explain which variables are most important in a random forests. Various variable importance measures are calculated and visualized in different settings in order to get an idea on how their importance changes depending on our criteria (Hemant Ishwaran and Udaya B. Kogalur and Eiran Z. Gorodeski and Andy J. Minn and Michael S. Lauer (2010) <doi:10.1198/jasa.2009.tm08622>, Leo Breiman (2001) <doi:10.1023/A:1010933404324>).

Maintained by Yue Jiang. Last updated 1 years ago.

random-forest

233 stars 9.59 score 236 scripts

cdriveraus

ctsem:Continuous Time Structural Equation Modelling

Hierarchical continuous (and discrete) time state space modelling, for linear and nonlinear systems measured by continuous variables, with limited support for binary data. The subject specific dynamic system is modelled as a stochastic differential equation (SDE) or difference equation, measurement models are typically multivariate normal factor models. Linear mixed effects SDE's estimated via maximum likelihood and optimization are the default. Nonlinearities, (state dependent parameters) and random effects on all parameters are possible, using either max likelihood / max a posteriori optimization (with optional importance sampling) or Stan's Hamiltonian Monte Carlo sampling. See <https://github.com/cdriveraus/ctsem/raw/master/vignettes/hierarchicalmanual.pdf> for details. Priors may be used. For the conceptual overview of the hierarchical Bayesian linear SDE approach, see <https://www.researchgate.net/publication/324093594_Hierarchical_Bayesian_Continuous_Time_Dynamic_Modeling>. Exogenous inputs may also be included, for an overview of such possibilities see <https://www.researchgate.net/publication/328221807_Understanding_the_Time_Course_of_Interventions_with_Continuous_Time_Dynamic_Models> . Stan based functions are not available on 32 bit Windows systems at present. <https://cdriver.netlify.app/> contains some tutorial blog posts.

Maintained by Charles Driver. Last updated 29 days ago.

stochastic-differential-equations time-series cpp

42 stars 9.58 score 366 scripts 1 dependents

bioc

recount:Explore and download data from the recount project

Explore and download data from the recount project available at https://jhubiostatistics.shinyapps.io/recount/. Using the recount package you can download RangedSummarizedExperiment objects at the gene, exon or exon-exon junctions level, the raw counts, the phenotype metadata used, the urls to the sample coverage bigWig files or the mean coverage bigWig file for a particular study. The RangedSummarizedExperiment objects can be used by different packages for performing differential expression analysis. Using http://bioconductor.org/packages/derfinder you can perform annotation-agnostic differential expression analyses with the data from the recount project as described at http://www.nature.com/nbt/journal/v35/n4/full/nbt.3838.html.

Maintained by Leonardo Collado-Torres. Last updated 4 months ago.

coverage differentialexpression geneexpression rnaseq sequencing software dataimport immunooncology annotation-agnostic bioconductor count derfinder deseq2 exon gene human illumina junction recount

41 stars 9.57 score 498 scripts 3 dependents

daattali

ddpcr:Analysis and Visualization of Droplet Digital PCR in R and on the Web

An interface to explore, analyze, and visualize droplet digital PCR (ddPCR) data in R. This is the first non-proprietary software for analyzing two-channel ddPCR data. An interactive tool was also created and is available online to facilitate this analysis for anyone who is not comfortable with using R.

Maintained by Dean Attali. Last updated 1 years ago.

61 stars 9.54 score 131 scripts 2 dependents

ndphillips

FFTrees:Generate, Visualise, and Evaluate Fast-and-Frugal Decision Trees

Create, visualize, and test fast-and-frugal decision trees (FFTs) using the algorithms and methods described by Phillips, Neth, Woike & Gaissmaier (2017), <doi:10.1017/S1930297500006239>. FFTs are simple and transparent decision trees for solving binary classification problems. FFTs can be preferable to more complex algorithms because they require very little information, are easy to understand and communicate, and are robust against overfitting.

Maintained by Hansjoerg Neth. Last updated 6 months ago.

136 stars 9.53 score 144 scripts

dcousin3

superb:Summary Plots with Adjusted Error Bars

Computes standard error and confidence interval of various descriptive statistics under various designs and sampling schemes. The main function, superb(), return a plot. It can also be used to obtain a dataframe with the statistics and their precision intervals so that other plotting environments (e.g., Excel) can be used. See Cousineau and colleagues (2021) <doi:10.1177/25152459211035109> or Cousineau (2017) <doi:10.5709/acp-0214-z> for a review as well as Cousineau (2005) <doi:10.20982/tqmp.01.1.p042>, Morey (2008) <doi:10.20982/tqmp.04.2.p061>, Baguley (2012) <doi:10.3758/s13428-011-0123-7>, Cousineau & Laurencelle (2016) <doi:10.1037/met0000055>, Cousineau & O'Brien (2014) <doi:10.3758/s13428-013-0441-z>, Calderini & Harding <doi:10.20982/tqmp.15.1.p001> for specific references.

Maintained by Denis Cousineau. Last updated 2 months ago.

error-bars plotting statistics summary-plots summary-statistics visualization

19 stars 9.53 score 155 scripts 2 dependents

immunomind

immunarch:Bioinformatics Analysis of T-Cell and B-Cell Immune Repertoires

A comprehensive framework for bioinformatics exploratory analysis of bulk and single-cell T-cell receptor and antibody repertoires. It provides seamless data loading, analysis and visualisation for AIRR (Adaptive Immune Receptor Repertoire) data, both bulk immunosequencing (RepSeq) and single-cell sequencing (scRNAseq). Immunarch implements most of the widely used AIRR analysis methods, such as: clonality analysis, estimation of repertoire similarities in distribution of clonotypes and gene segments, repertoire diversity analysis, annotation of clonotypes using external immune receptor databases and clonotype tracking in vaccination and cancer studies. A successor to our previously published 'tcR' immunoinformatics package (Nazarov 2015) <doi:10.1186/s12859-015-0613-1>.

Maintained by Vadim I. Nazarov. Last updated 1 years ago.

airr-analysis b-cell-receptor bcr bcr-repertoire bioinformatics ig ig-repertoire immune-repertoire immune-repertoire-analysis immune-repertoire-data immunoglobulin immunoinformatics immunology rep-seq repertoire-analysis single-cell single-cell-analysis t-cell-receptor tcr tcr-repertoire cpp

316 stars 9.49 score 203 scripts

jamovi

jmv:The 'jamovi' Analyses

A suite of common statistical methods such as descriptives, t-tests, ANOVAs, regression, correlation matrices, proportion tests, contingency tables, and factor analysis. This package is also useable from the 'jamovi' statistical spreadsheet (see <https://www.jamovi.org> for more information).

Maintained by Jonathon Love. Last updated 1 months ago.

60 stars 9.48 score 440 scripts

shixiangwang

sigminer:Extract, Analyze and Visualize Mutational Signatures for Genomic Variations

Genomic alterations including single nucleotide substitution, copy number alteration, etc. are the major force for cancer initialization and development. Due to the specificity of molecular lesions caused by genomic alterations, we can generate characteristic alteration spectra, called 'signature' (Wang, Shixiang, et al. (2021) <DOI:10.1371/journal.pgen.1009557> & Alexandrov, Ludmil B., et al. (2020) <DOI:10.1038/s41586-020-1943-3> & Steele Christopher D., et al. (2022) <DOI:10.1038/s41586-022-04738-6>). This package helps users to extract, analyze and visualize signatures from genomic alteration records, thus providing new insight into cancer study.

Maintained by Shixiang Wang. Last updated 6 months ago.

bayesian-nmf bioinformatics cancer-research cnv copynumber-signatures cosmic-signatures dbs easy-to-use indel mutational-signatures nmf nmf-extraction sbs signature-extraction somatic-mutations somatic-variants visualization cpp

150 stars 9.48 score 123 scripts 2 dependents

stemangiola

tidyseurat:Brings Seurat to the Tidyverse

It creates an invisible layer that allow to see the 'Seurat' object as tibble and interact seamlessly with the tidyverse.

Maintained by Stefano Mangiola. Last updated 8 months ago.

assaydomain infrastructure rnaseq differentialexpression geneexpression normalization clustering qualitycontrol sequencing transcription transcriptomics dplyr ggplot2 pca purrr sct seurat single-cell single-cell-rna-seq tibble tidyr tidyverse transcripts tsne umap

159 stars 9.48 score 398 scripts 1 dependents

nepem-ufsc

metan:Multi Environment Trials Analysis

Performs stability analysis of multi-environment trial data using parametric and non-parametric methods. Parametric methods includes Additive Main Effects and Multiplicative Interaction (AMMI) analysis by Gauch (2013) <doi:10.2135/cropsci2013.04.0241>, Ecovalence by Wricke (1965), Genotype plus Genotype-Environment (GGE) biplot analysis by Yan & Kang (2003) <doi:10.1201/9781420040371>, geometric adaptability index by Mohammadi & Amri (2008) <doi:10.1007/s10681-007-9600-6>, joint regression analysis by Eberhart & Russel (1966) <doi:10.2135/cropsci1966.0011183X000600010011x>, genotypic confidence index by Annicchiarico (1992), Murakami & Cruz's (2004) method, power law residuals (POLAR) statistics by Doring et al. (2015) <doi:10.1016/j.fcr.2015.08.005>, scale-adjusted coefficient of variation by Doring & Reckling (2018) <doi:10.1016/j.eja.2018.06.007>, stability variance by Shukla (1972) <doi:10.1038/hdy.1972.87>, weighted average of absolute scores by Olivoto et al. (2019a) <doi:10.2134/agronj2019.03.0220>, and multi-trait stability index by Olivoto et al. (2019b) <doi:10.2134/agronj2019.03.0221>. Non-parametric methods includes superiority index by Lin & Binns (1988) <doi:10.4141/cjps88-018>, nonparametric measures of phenotypic stability by Huehn (1990) <doi:10.1007/BF00024241>, TOP third statistic by Fox et al. (1990) <doi:10.1007/BF00040364>. Functions for computing biometrical analysis such as path analysis, canonical correlation, partial correlation, clustering analysis, and tools for inspecting, manipulating, summarizing and plotting typical multi-environment trial data are also provided.

Maintained by Tiago Olivoto. Last updated 27 days ago.

2 stars 9.48 score 1.3k scripts 2 dependents

trinker

qdap:Bridging the Gap Between Qualitative Data and Quantitative Analysis

Automates many of the tasks associated with quantitative discourse analysis of transcripts containing discourse including frequency counts of sentence types, words, sentences, turns of talk, syllables and other assorted analysis tasks. The package provides parsing tools for preparing transcript data. Many functions enable the user to aggregate data by any number of grouping variables, providing analysis and seamless integration with other R packages that undertake higher level analysis and visualization of text. This affords the user a more efficient and targeted analysis. 'qdap' is designed for transcript analysis, however, many functions are applicable to other areas of Text Mining/ Natural Language Processing.

Maintained by Tyler Rinker. Last updated 5 years ago.

qdap quantitative-discourse-analysis text-analysis text-mining text-plotting openjdk

176 stars 9.47 score 1.3k scripts 3 dependents

mfasiolo

mgcViz:Visualisations for Generalized Additive Models

Extension of the 'mgcv' package, providing visual tools for Generalized Additive Models that exploit the additive structure of such models, scale to large data sets and can be used in conjunction with a wide range of response distributions. The focus is providing visual methods for better understanding the model output and for aiding model checking and development beyond simple exponential family regression. The graphical framework is based on the layering system provided by 'ggplot2'.

Maintained by Matteo Fasiolo. Last updated 16 days ago.

78 stars 9.42 score 1000 scripts

bioc

DEGreport:Report of DEG analysis

Creation of ready-to-share figures of differential expression analyses of count data. It integrates some of the code mentioned in DESeq2 and edgeR vignettes, and report a ranked list of genes according to the fold changes mean and variability for each selected gene.

Maintained by Lorena Pantano. Last updated 5 months ago.

differentialexpression visualization rnaseq reportwriting geneexpression immunooncology bioconductor differential-expression qc report rna-seq smallrna

24 stars 9.42 score 354 scripts 1 dependents

sizespectrum

mizer:Dynamic Multi-Species Size Spectrum Modelling

A set of classes and methods to set up and run multi-species, trait based and community size spectrum ecological models, focused on the marine environment.

Maintained by Gustav Delius. Last updated 2 months ago.

ecosystem-model fish-population-dynamics fisheries fisheries-management marine-ecosystem population-dynamics simulation size-structure species-interactions transport-equation cpp

39 stars 9.41 score 207 scripts

usepa

tcpl:ToxCast Data Analysis Pipeline

The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, 'invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but 'tcpl' can be used to support diverse chemical screening efforts.

Maintained by Jason Brown. Last updated 1 days ago.

ccte comptox ord

36 stars 9.41 score 90 scripts

cjendres1

nhanesA:NHANES Data Retrieval

Utility to retrieve data from the National Health and Nutrition Examination Survey (NHANES) website <https://www.cdc.gov/nchs/nhanes/>.

Maintained by Christopher Endres. Last updated 3 months ago.

nhanes

59 stars 9.37 score 239 scripts

briencj

asremlPlus:Augments 'ASReml-R' in Fitting Mixed Models and Packages Generally in Exploring Prediction Differences

Assists in automating the selection of terms to include in mixed models when 'asreml' is used to fit the models. Procedures are available for choosing models that conform to the hierarchy or marginality principle, for fitting and choosing between two-dimensional spatial models using correlation, natural cubic smoothing spline and P-spline models. A history of the fitting of a sequence of models is kept in a data frame. Also used to compute functions and contrasts of, to investigate differences between and to plot predictions obtained using any model fitting function. The content falls into the following natural groupings: (i) Data, (ii) Model modification functions, (iii) Model selection and description functions, (iv) Model diagnostics and simulation functions, (v) Prediction production and presentation functions, (vi) Response transformation functions, (vii) Object manipulation functions, and (viii) Miscellaneous functions (for further details see 'asremlPlus-package' in help). The 'asreml' package provides a computationally efficient algorithm for fitting a wide range of linear mixed models using Residual Maximum Likelihood. It is a commercial package and a license for it can be purchased from 'VSNi' <https://vsni.co.uk/> as 'asreml-R', who will supply a zip file for local installation/updating (see <https://asreml.kb.vsni.co.uk/>). It is not needed for functions that are methods for 'alldiffs' and 'data.frame' objects. The package 'asremPlus' can also be installed from <http://chris.brien.name/rpackages/>.

Maintained by Chris Brien. Last updated 2 months ago.

asreml mixed-models

19 stars 9.37 score 200 scripts

eblondel

rsdmx:Tools for Reading SDMX Data and Metadata

Set of classes and methods to read data and metadata documents exchanged through the Statistical Data and Metadata Exchange (SDMX) framework, currently focusing on the SDMX XML standard format (SDMX-ML).

Maintained by Emmanuel Blondel. Last updated 2 days ago.

api datastructures dsd read readsdmx sdmx sdmx-format sdmx-provider sdmx-standards statistics timeseries web-services

105 stars 9.36 score 4 dependents

matthias-da

robCompositions:Compositional Data Analysis

Methods for analysis of compositional data including robust methods (<doi:10.1007/978-3-319-96422-5>), imputation of missing values (<doi:10.1016/j.csda.2009.11.023>), methods to replace rounded zeros (<doi:10.1080/02664763.2017.1410524>, <doi:10.1016/j.chemolab.2016.04.011>, <doi:10.1016/j.csda.2012.02.012>), count zeros (<doi:10.1177/1471082X14535524>), methods to deal with essential zeros (<doi:10.1080/02664763.2016.1182135>), (robust) outlier detection for compositional data, (robust) principal component analysis for compositional data, (robust) factor analysis for compositional data, (robust) discriminant analysis for compositional data (Fisher rule), robust regression with compositional predictors, functional data analysis (<doi:10.1016/j.csda.2015.07.007>) and p-splines (<doi:10.1016/j.csda.2015.07.007>), contingency (<doi:10.1080/03610926.2013.824980>) and compositional tables (<doi:10.1111/sjos.12326>, <doi:10.1111/sjos.12223>, <doi:10.1080/02664763.2013.856871>) and (robust) Anderson-Darling normality tests for compositional data as well as popular log-ratio transformations (addLR, cenLR, isomLR, and their inverse transformations). In addition, visualisation and diagnostic tools are implemented as well as high and low-level plot functions for the ternary diagram.

Maintained by Matthias Templ. Last updated 2 days ago.

cpp

11 stars 9.36 score 226 scripts 2 dependents

ecospat

ecospat:Spatial Ecology Miscellaneous Methods

Collection of R functions and data sets for the support of spatial ecology analyses with a focus on pre, core and post modelling analyses of species distribution, niche quantification and community assembly. Written by current and former members and collaborators of the ecospat group of Antoine Guisan, Department of Ecology and Evolution (DEE) and Institute of Earth Surface Dynamics (IDYST), University of Lausanne, Switzerland. Read Di Cola et al. (2016) <doi:10.1111/ecog.02671> for details.

Maintained by Olivier Broennimann. Last updated 2 months ago.

32 stars 9.35 score 418 scripts 1 dependents

cbielow

PTXQC:Quality Report Generation for MaxQuant and mzTab Results

Generates Proteomics (PTX) quality control (QC) reports for shotgun LC-MS data analyzed with the MaxQuant software suite (from .txt files) or mzTab files (ideally from OpenMS 'QualityControl' tool). Reports are customizable (target thresholds, subsetting) and available in HTML or PDF format. Published in J. Proteome Res., Proteomics Quality Control: Quality Control Software for MaxQuant Results (2015) <doi:10.1021/acs.jproteome.5b00780>.

Maintained by Chris Bielow. Last updated 1 years ago.

drag-and-drop hacktoberfest heatmap match-between-runs maxquant metric mztab openms proteomics quality-control quality-metrics report

42 stars 9.35 score 105 scripts 1 dependents

bioc

LOLA:Locus overlap analysis for enrichment of genomic ranges

Provides functions for testing overlap of sets of genomic regions with public and custom region set (genomic ranges) databases. This makes it possible to do automated enrichment analysis for genomic region sets, thus facilitating interpretation of functional genomics and epigenomics data.

Maintained by Nathan Sheffield. Last updated 5 months ago.

genesetenrichment generegulation genomeannotation systemsbiology functionalgenomics chipseq methylseq sequencing

76 stars 9.34 score 160 scripts

pecanproject

PEcAn.data.land:PEcAn Functions Used for Ecological Forecasts and Reanalysis

The Predictive Ecosystem Carbon Analyzer (PEcAn) is a scientific workflow management tool that is designed to simplify the management of model parameterization, execution, and analysis. The goal of PECAn is to streamline the interaction between data and models, and to improve the efficacy of scientific investigation.

Maintained by Mike Dietze. Last updated 2 days ago.

bayesian cyberinfrastructure data-assimilation data-science ecosystem-model ecosystem-science forecasting meta-analysis national-science-foundation pecan plants jags cpp

216 stars 9.34 score 19 scripts 10 dependents

dmphillippo

multinma:Bayesian Network Meta-Analysis of Individual and Aggregate Data

Network meta-analysis and network meta-regression models for aggregate data, individual patient data, and mixtures of both individual and aggregate data using multilevel network meta-regression as described by Phillippo et al. (2020) <doi:10.1111/rssa.12579>. Models are estimated in a Bayesian framework using 'Stan'.

Maintained by David M. Phillippo. Last updated 8 days ago.

statistics cpp

35 stars 9.34 score 163 scripts

rte-antares-rpackage

antaresRead:Import, Manipulate and Explore the Results of an 'Antares' Simulation

Import, manipulate and explore results generated by 'Antares', a powerful open source software developed by RTE (Réseau de Transport d’Électricité) to simulate and study electric power systems (more information about 'Antares' here : <https://antares-simulator.org/>).

Maintained by Tatiana Vargas. Last updated 8 days ago.

infrastructure dataimport adequacy bilan electricity energy hdf5 linear-algebra monte-carlo-simulation optimisation previsionnel rhdf5 rte simulation tyndp

13 stars 9.32 score 148 scripts 3 dependents

microsoft

finnts:Microsoft Finance Time Series Forecasting Framework

Automated time series forecasting developed by Microsoft Finance. The Microsoft Finance Time Series Forecasting Framework, aka Finn, can be used to forecast any component of the income statement, balance sheet, or any other area of interest by finance. Any numerical quantity over time, Finn can be used to forecast it. While it can be applied outside of the finance domain, Finn was built to meet the needs of financial analysts to better forecast their businesses within a company, and has a lot of built in features that are specific to the needs of financial forecasters. Happy forecasting!

Maintained by Mike Tokic. Last updated 1 months ago.

business data-science feature-selection finance finnts forecasting machine-learning microsoft time-series

194 stars 9.30 score 39 scripts

gojiplus

tuber:Client for the YouTube API

Get comments posted on YouTube videos, information on how many times a video has been liked, search for videos with particular content, and much more. You can also scrape captions from a few videos. To learn more about the YouTube API, see <https://developers.google.com/youtube/v3/>.

Maintained by Gaurav Sood. Last updated 1 days ago.

access-youtube caption video youtube youtube-api youtube-oauth

185 stars 9.29 score 206 scripts

bioc

EWCE:Expression Weighted Celltype Enrichment

Used to determine which cell types are enriched within gene lists. The package provides tools for testing enrichments within simple gene lists (such as human disease associated genes) and those resulting from differential expression studies. The package does not depend upon any particular Single Cell Transcriptome dataset and user defined datasets can be loaded in and used in the analyses.

Maintained by Alan Murphy. Last updated 2 months ago.

geneexpression transcription differentialexpression genesetenrichment genetics microarray mrnamicroarray onechannel rnaseq biomedicalinformatics proteomics visualization functionalgenomics singlecell deconvolution single-cell single-cell-rna-seq transcriptomics

56 stars 9.29 score 99 scripts

sbegueria

SPEI:Calculation of the Standardized Precipitation-Evapotranspiration Index

A set of functions for computing potential evapotranspiration and several widely used drought indices including the Standardized Precipitation-Evapotranspiration Index (SPEI).

Maintained by Santiago Beguería. Last updated 2 days ago.

82 stars 9.28 score 314 scripts 20 dependents

brianstock

MixSIAR:Bayesian Mixing Models in R

Creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). 'MixSIAR' is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. 'MixSIAR' incorporates several years of advances since 'MixSIR' and 'SIAR'.

Maintained by Brian Stock. Last updated 4 years ago.

jags cpp

98 stars 9.27 score 122 scripts

bioc

IsoformSwitchAnalyzeR:Identify, Annotate and Visualize Isoform Switches with Functional Consequences from both short- and long-read RNA-seq data

Analysis of alternative splicing and isoform switches with predicted functional consequences (e.g. gain/loss of protein domains etc.) from quantification of all types of RNASeq by tools such as Kallisto, Salmon, StringTie, Cufflinks/Cuffdiff etc.

Maintained by Kristoffer Vitting-Seerup. Last updated 5 months ago.

geneexpression transcription alternativesplicing differentialexpression differentialsplicing visualization statisticalmethod transcriptomevariant biomedicalinformatics functionalgenomics systemsbiology transcriptomics rnaseq annotation functionalprediction geneprediction dataimport multiplecomparison batcheffect immunooncology

108 stars 9.26 score 125 scripts

aphalo

photobiology:Photobiological Calculations

Definitions of classes, methods, operators and functions for use in photobiology and radiation meteorology and climatology. Calculation of effective (weighted) and not-weighted irradiances/doses, fluence rates, transmittance, reflectance, absorptance, absorbance and diverse ratios and other derived quantities from spectral data. Local maxima and minima: peaks, valleys and spikes. Conversion between energy-and photon-based units. Wavelength interpolation. Astronomical calculations related solar angles and day length. Colours and vision. This package is part of the 'r4photobiology' suite, Aphalo, P. J. (2015) <doi:10.19232/uv4pb.2015.1.14>.

Maintained by Pedro J. Aphalo. Last updated 4 days ago.

light photobiology quantification r4photobiology-suite radiation spectra sun-position

4 stars 9.20 score 604 scripts 12 dependents

isglobal-brge

SNPassoc:SNPs-Based Whole Genome Association Studies

Functions to perform most of the common analysis in genome association studies are implemented. These analyses include descriptive statistics and exploratory analysis of missing values, calculation of Hardy-Weinberg equilibrium, analysis of association based on generalized linear models (either for quantitative or binary traits), and analysis of multiple SNPs (haplotype and epistasis analysis). Permutation test and related tests (sum statistic and truncated product) are also implemented. Max-statistic and genetic risk-allele score exact distributions are also possible to be estimated. The methods are described in Gonzalez JR et al., 2007 <doi: 10.1093/bioinformatics/btm025>.

Maintained by Dolors Pelegri. Last updated 5 months ago.

16 stars 9.11 score 89 scripts 6 dependents

prodriguezsosa

conText:'a la Carte' on Text (ConText) Embedding Regression

A fast, flexible and transparent framework to estimate context-specific word and short document embeddings using the 'a la carte' embeddings approach developed by Khodak et al. (2018) <arXiv:1805.05388> and evaluate hypotheses about covariate effects on embeddings using the regression framework developed by Rodriguez et al. (2021)<https://github.com/prodriguezsosa/EmbeddingRegression>.

Maintained by Pedro L. Rodriguez. Last updated 12 months ago.

104 stars 9.10 score 1.7k scripts

didiermurillof

FielDHub:A Shiny App for Design of Experiments in Life Sciences

A shiny design of experiments (DOE) app that aids in the creation of traditional, un-replicated, augmented and partially-replicated designs applied to agriculture, plant breeding, forestry, animal and biological sciences.

Maintained by Didier Murillo. Last updated 8 months ago.

agricultural breeding design doe experimental plantbreeding shiny

47 stars 9.09 score 70 scripts 1 dependents

ryanhope

Rmisc:Rmisc: Ryan Miscellaneous

The Rmisc library contains many functions useful for data analysis and utility operations.

Maintained by Ryan M. Hope. Last updated 11 years ago.

2 stars 9.09 score 5.6k scripts 8 dependents

bioc

sesame:SEnsible Step-wise Analysis of DNA MEthylation BeadChips

Tools For analyzing Illumina Infinium DNA methylation arrays. SeSAMe provides utilities to support analyses of multiple generations of Infinium DNA methylation BeadChips, including preprocessing, quality control, visualization and inference. SeSAMe features accurate detection calling, intelligent inference of ethnicity, sex and advanced quality control routines.

Maintained by Wanding Zhou. Last updated 3 months ago.

dnamethylation methylationarray preprocessing qualitycontrol bioinformatics dna-methylation microarray

69 stars 9.08 score 258 scripts 1 dependents

bioc

OUTRIDER:OUTRIDER - OUTlier in RNA-Seq fInDER

Identification of aberrant gene expression in RNA-seq data. Read count expectations are modeled by an autoencoder to control for confounders in the data. Given these expectations, the RNA-seq read counts are assumed to follow a negative binomial distribution with a gene-specific dispersion. Outliers are then identified as read counts that significantly deviate from this distribution. Furthermore, OUTRIDER provides useful plotting functions to analyze and visualize the results.

Maintained by Christian Mertes. Last updated 5 months ago.

immunooncology rnaseq transcriptomics alignment sequencing geneexpression genetics count-data diagnostics expression-analysis mendelian-genetics outlier-detection rna-seq openblas cpp

50 stars 9.07 score 110 scripts 1 dependents

cmmr

rbiom:Read/Write, Analyze, and Visualize 'BIOM' Data

A toolkit for working with Biological Observation Matrix ('BIOM') files. Read/write all 'BIOM' formats. Compute rarefaction, alpha diversity, and beta diversity (including 'UniFrac'). Summarize counts by taxonomic level. Subset based on metadata. Generate visualizations and statistical analyses. CPU intensive operations are coded in C for speed.

Maintained by Daniel P. Smith. Last updated 16 days ago.

15 stars 9.07 score 117 scripts 6 dependents

cardiomoon

ggiraphExtra:Make Interactive 'ggplot2'. Extension to 'ggplot2' and 'ggiraph'

Collection of functions to enhance 'ggplot2' and 'ggiraph'. Provides functions for exploratory plots. All plot can be a 'static' plot or an 'interactive' plot using 'ggiraph'.

Maintained by Keon-Woong Moon. Last updated 4 years ago.

48 stars 9.07 score 402 scripts 3 dependents

bioc

BatchQC:Batch Effects Quality Control Software

Sequencing and microarray samples often are collected or processed in multiple batches or at different times. This often produces technical biases that can lead to incorrect results in the downstream analysis. BatchQC is a software tool that streamlines batch preprocessing and evaluation by providing interactive diagnostics, visualizations, and statistical analyses to explore the extent to which batch variation impacts the data. BatchQC diagnostics help determine whether batch adjustment needs to be done, and how correction should be applied before proceeding with a downstream analysis. Moreover, BatchQC interactively applies multiple common batch effect approaches to the data and the user can quickly see the benefits of each method. BatchQC is developed as a Shiny App. The output is organized into multiple tabs and each tab features an important part of the batch effect analysis and visualization of the data. The BatchQC interface has the following analysis groups: Summary, Differential Expression, Median Correlations, Heatmaps, Circular Dendrogram, PCA Analysis, Shape, ComBat and SVA.

Maintained by Jessica Anderson. Last updated 15 days ago.

batcheffect graphandnetwork microarray normalization principalcomponent sequencing software visualization qualitycontrol rnaseq preprocessing differentialexpression immunooncology

7 stars 9.06 score 54 scripts

gleon

rLakeAnalyzer:Lake Physics Tools

Standardized methods for calculating common important derived physical features of lakes including water density based based on temperature, thermal layers, thermocline depth, lake number, Wedderburn number, Schmidt stability and others.

Maintained by Luke Winslow. Last updated 4 years ago.

45 stars 9.05 score 280 scripts 1 dependents