Showing 52 of total 52 results (show query)

brodieg

diffobj:Diffs for R Objects

Generate a colorized diff of two R objects for an intuitive visualization of their differences.

Maintained by Brodie Gaslam. Last updated 3 years ago.

diff

231 stars 13.17 score 107 scripts 494 dependents

edzer

intervals:Tools for Working with Points and Intervals

Tools for working with and comparing sets of points and intervals.

Maintained by Edzer Pebesma. Last updated 7 months ago.

cpp

11 stars 9.50 score 122 scripts 98 dependents

bioc

qusage:qusage: Quantitative Set Analysis for Gene Expression

This package is an implementation the Quantitative Set Analysis for Gene Expression (QuSAGE) method described in (Yaari G. et al, Nucl Acids Res, 2013). This is a novel Gene Set Enrichment-type test, which is designed to provide a faster, more accurate, and easier to understand test for gene expression studies. qusage accounts for inter-gene correlations using the Variance Inflation Factor technique proposed by Wu et al. (Nucleic Acids Res, 2012). In addition, rather than simply evaluating the deviation from a null hypothesis with a single number (a P value), qusage quantifies gene set activity with a complete probability density function (PDF). From this PDF, P values and confidence intervals can be easily extracted. Preserving the PDF also allows for post-hoc analysis (e.g., pair-wise comparisons of gene set activity) while maintaining statistical traceability. Finally, while qusage is compatible with individual gene statistics from existing methods (e.g., LIMMA), a Welch-based method is implemented that is shown to improve specificity. The QuSAGE package also includes a mixed effects model implementation, as described in (Turner JA et al, BMC Bioinformatics, 2015), and a meta-analysis framework as described in (Meng H, et al. PLoS Comput Biol. 2019). For questions, contact Chris Bolen (cbolen1@gmail.com) or Steven Kleinstein (steven.kleinstein@yale.edu)

Maintained by Christopher Bolen. Last updated 5 months ago.

genesetenrichmentmicroarrayrnaseqsoftwareimmunooncology

5.65 score 185 scripts 1 dependents

anainesvs

pedigreemm:Pedigree-Based Mixed-Effects Models

Fit pedigree-based mixed-effects models.

Maintained by Ana Ines Vazquez. Last updated 1 years ago.

1 stars 5.42 score 87 scripts 2 dependents

robinhankin

multivator:A Multivariate Emulator

A multivariate generalization of the emulator package.

Maintained by Robin K. S. Hankin. Last updated 2 years ago.

3.62 score 21 scripts