Showing 8 of total 8 results (show query)
metrumresearchgroup
mrgsolve:Simulate from ODE-Based Models
Fast simulation from ordinary differential equation (ODE) based models typically employed in quantitative pharmacology and systems biology.
Maintained by Kyle T Baron. Last updated 30 days ago.
65.3 match 138 stars 10.90 score 1.2k scripts 3 dependents
calvagone
campsismod:Generic Implementation of a PK/PD Model
A generic, easy-to-use and expandable implementation of a pharmacokinetic (PK) / pharmacodynamic (PD) model based on the S4 class system. This package allows the user to read/write a pharmacometric model from/to files and adapt it further on the fly in the R environment. For this purpose, this package provides an intuitive API to add, modify or delete equations, ordinary differential equations (ODE's), model parameters or compartment properties (like infusion duration or rate, bioavailability and initial values). Finally, this package also provides a useful export of the model for use with simulation packages 'rxode2' and 'mrgsolve'. This package is designed and intended to be used with package 'campsis', a PK/PD simulation platform built on top of 'rxode2' and 'mrgsolve'.
Maintained by Nicolas Luyckx. Last updated 1 months ago.
18.8 match 5 stars 6.64 score 42 scripts 1 dependents
kylebaron
mrgsim.parallel:Simulate with 'mrgsolve' in Parallel
Simulation from an 'mrgsolve' <https://cran.r-project.org/package=mrgsolve> model using a parallel backend. Input data sets are split (chunked) and simulated in parallel using mclapply() or future_lapply() <https://cran.r-project.org/package=future.apply>.
Maintained by Kyle Baron. Last updated 3 months ago.
16.1 match 5 stars 5.11 score 17 scripts
smouksassi
coveffectsplot:Produce Forest Plots to Visualize Covariate Effects
Produce forest plots to visualize covariate effects using either the command line or an interactive 'Shiny' application.
Maintained by Samer Mouksassi. Last updated 1 months ago.
4.7 match 32 stars 7.86 score 40 scriptskylebaron
mrgsim.sa:Sensitivity Analysis with 'mrgsolve'
Perform sensitivity analysis on ordinary differential equation based models, including ad-hoc graphical analyses based on structured sequences of parameters as well as local sensitivity analysis. Functions are provided for creating inputs, simulating scenarios and plotting outputs.
Maintained by Kyle Baron. Last updated 1 years ago.
7.0 match 6 stars 5.05 score 37 scriptscalvagone
campsis:Generic PK/PD Simulation Platform CAMPSIS
A generic, easy-to-use and intuitive pharmacokinetic/pharmacodynamic (PK/PD) simulation platform based on R packages 'rxode2' and 'mrgsolve'. CAMPSIS provides an abstraction layer over the underlying processes of writing a PK/PD model, assembling a custom dataset and running a simulation. CAMPSIS has a strong dependency to the R package 'campsismod', which allows to read/write a model from/to files and adapt it further on the fly in the R environment. Package 'campsis' allows the user to assemble a dataset in an intuitive manner. Once the user’s dataset is ready, the package is in charge of preparing the simulation, calling 'rxode2' or 'mrgsolve' (at the user's choice) and returning the results, for the given model, dataset and desired simulation settings.
Maintained by Nicolas Luyckx. Last updated 1 months ago.
4.4 match 8 stars 7.52 score 93 scripts
cran
pmxcode:Create Pharmacometric Models
Provides a user interface to create or modify pharmacometric models for various modeling and simulation software platforms.
Maintained by Sebastien Bihorel. Last updated 14 days ago.
5.6 match 1 stars 3.18 score
felicienll
mapbayr:MAP-Bayesian Estimation of PK Parameters
Performs maximum a posteriori Bayesian estimation of individual pharmacokinetic parameters from a model defined in 'mrgsolve', typically for model-based therapeutic drug monitoring. Internally computes an objective function value from model and data, performs optimization and returns predictions in a convenient format. The performance of the package was described by Le Louedec et al (2021) <doi:10.1002/psp4.12689>.
Maintained by Felicien Le Louedec. Last updated 2 years ago.
0.5 match 21 stars 4.55 score 34 scripts