Showing 11 of total 11 results (show query)
branchlab
metasnf:Meta Clustering with Similarity Network Fusion
Framework to facilitate patient subtyping with similarity network fusion and meta clustering. The similarity network fusion (SNF) algorithm was introduced by Wang et al. (2014) in <doi:10.1038/nmeth.2810>. SNF is a data integration approach that can transform high-dimensional and diverse data types into a single similarity network suitable for clustering with minimal loss of information from each initial data source. The meta clustering approach was introduced by Caruana et al. (2006) in <doi:10.1109/ICDM.2006.103>. Meta clustering involves generating a wide range of cluster solutions by adjusting clustering hyperparameters, then clustering the solutions themselves into a manageable number of qualitatively similar solutions, and finally characterizing representative solutions to find ones that are best for the user's specific context. This package provides a framework to easily transform multi-modal data into a wide range of similarity network fusion-derived cluster solutions as well as to visualize, characterize, and validate those solutions. Core package functionality includes easy customization of distance metrics, clustering algorithms, and SNF hyperparameters to generate diverse clustering solutions; calculation and plotting of associations between features, between patients, and between cluster solutions; and standard cluster validation approaches including resampled measures of cluster stability, standard metrics of cluster quality, and label propagation to evaluate generalizability in unseen data. Associated vignettes guide the user through using the package to identify patient subtypes while adhering to best practices for unsupervised learning.
Maintained by Prashanth S Velayudhan. Last updated 3 days ago.
bioinformaticsclusteringmetaclusteringsnf
46.3 match 8 stars 8.21 score 30 scriptsconeill-math
m2r:Interface to 'Macaulay2'
Persistent interface to 'Macaulay2' <http://www.math.uiuc.edu/Macaulay2/> and front-end tools facilitating its use in the 'R' ecosystem. For details see Kahle et. al. (2020) <doi:10.18637/jss.v093.i09>.
Maintained by David Kahle. Last updated 5 years ago.
6.3 match 5 stars 5.23 score 34 scriptssharifrahmanie
MBMethPred:Medulloblastoma Subgroups Prediction
Utilizing a combination of machine learning models (Random Forest, Naive Bayes, K-Nearest Neighbor, Support Vector Machines, Extreme Gradient Boosting, and Linear Discriminant Analysis) and a deep Artificial Neural Network model, 'MBMethPred' can predict medulloblastoma subgroups, including wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4 from DNA methylation beta values. See Sharif Rahmani E, Lawarde A, Lingasamy P, Moreno SV, Salumets A and Modhukur V (2023), MBMethPred: a computational framework for the accurate classification of childhood medulloblastoma subgroups using data integration and AI-based approaches. Front. Genet. 14:1233657. <doi: 10.3389/fgene.2023.1233657> for more details.
Maintained by Edris Sharif Rahmani. Last updated 1 years ago.
6.0 match 3.70 score 1 scriptscran
SNFtool:Similarity Network Fusion
Similarity Network Fusion takes multiple views of a network and fuses them together to construct an overall status matrix. The input to our algorithm can be feature vectors, pairwise distances, or pairwise similarities. The learned status matrix can then be used for retrieval, clustering, and classification.
Maintained by Benjamin Brew. Last updated 4 years ago.
3.3 match 19 stars 4.31 score 4 dependentsbioc
CiteFuse:CiteFuse: multi-modal analysis of CITE-seq data
CiteFuse pacakage implements a suite of methods and tools for CITE-seq data from pre-processing to integrative analytics, including doublet detection, network-based modality integration, cell type clustering, differential RNA and protein expression analysis, ADT evaluation, ligand-receptor interaction analysis, and interactive web-based visualisation of the analyses.
Maintained by Yingxin Lin. Last updated 5 months ago.
singlecellgeneexpressionbioinformaticssingle-cellcpp
1.5 match 27 stars 6.59 score 18 scriptsenricoschumann
SNSFdatasets:Download Datasets from the Swiss National Science Foundation (SNF, FNS, SNSF)
Download and read datasets from the Swiss National Science Foundation (SNF, FNS, SNSF; <https://snf.ch>). The package is lightweight and without dependencies. Downloaded data can optionally be cached, to avoid repeated downloads of the same files. There are also utilities for comparing different versions of datasets, i.e. to report added, removed and changed entries.
Maintained by Enrico Schumann. Last updated 1 years ago.
3.6 match 2.70 scoreleef-uzh
LEEF:Data Package Containing Only Data and Data Information
Setup package for the LEEF pipeline which loads / installs all necessary packages and functions to run the pipeline.
Maintained by Rainer M. Krug. Last updated 3 years ago.
data-analysisdata-processingleef
1.7 match 2.95 scoreleef-uzh
LEEF.analysis:Access Functions, Tests and Basic Analysis of the RRD Data from the LEEF Project
Provides simple access functions to read data out of the sqlite RRD database. SQL queries can be configured in a yaml config file and used.
Maintained by Rainer M. Krug. Last updated 1 months ago.
1.7 match 2.44 score 23 scriptsleef-uzh
LEEF.measurement.flowcytometer:What the Package Does (Title Case)
More about what it does (maybe more than one line) Use four spaces when indenting paragraphs within the Description.
Maintained by Rainer M. Krug. Last updated 3 years ago.
1.7 match 1.48 score 2 scripts 1 dependentsleef-uzh
LEEF.measurement.bemovi:Prepares Movies for Analysis with Bemovi and Extracts Data
Module for the LEEF pipeline to process bemovi data.
Maintained by Rainer M. Krug. Last updated 3 years ago.
1.7 match 1.48 score 1 dependentsleef-uzh
LEEF.measurement.flowcam:Pre-Process and Extract Flowcam Data
More about what it does (maybe more than one line) Use four spaces when indenting paragraphs within the Description.
Maintained by Rainer M. Krug. Last updated 3 years ago.
1.7 match 1.48 score 1 dependents