Showing 14 of total 14 results (show query)

mskcc-epi-bio

PROscorerTools:Tools to Score Patient-Reported Outcome (PRO) and Other Psychometric Measures

Provides a reliable and flexible toolbox to score patient-reported outcome (PRO), Quality of Life (QOL), and other psychometric measures. The guiding philosophy is that scoring errors can be eliminated by using a limited number of well-tested, well-behaved functions to score PRO-like measures. The workhorse of the package is the 'scoreScale' function, which can be used to score most single-scale measures. It can reverse code items that need to be reversed before scoring and pro-rate scores for missing item data. Currently, three different types of scores can be output: summed item scores, mean item scores, and scores scaled to range from 0 to 100. The 'PROscorerTools' functions can be used to write new functions that score more complex measures. In fact, 'PROscorerTools' functions are the building blocks of the scoring functions in the 'PROscorer' package (which is a repository of functions that score specific commonly-used instruments). Users are encouraged to use 'PROscorerTools' to write scoring functions for their favorite PRO-like instruments, and to submit these functions for inclusion in 'PROscorer' (a tutorial vignette will be added soon). The long-term vision for the 'PROscorerTools' and 'PROscorer' packages is to provide an easy-to-use system to facilitate the incorporation of PRO measures into research studies in a scientifically rigorous and reproducible manner. These packages and their vignettes are intended to help establish and promote "best practices" for scoring and describing PRO-like measures in research.

Maintained by Ray Baser. Last updated 1 years ago.

clinical-trialsprospsychometricsqolquality-of-lifequestionnairesurvey

11.0 match 2 stars 4.73 score 18 scripts 1 dependents

bioconductor

BiocManager:Access the Bioconductor Project Package Repository

A convenient tool to install and update Bioconductor packages.

Maintained by Marcel Ramos. Last updated 1 months ago.

core-services

1.5 match 74 stars 16.47 score 2.9k scripts 414 dependents

bioc

pathwayPCA:Integrative Pathway Analysis with Modern PCA Methodology and Gene Selection

pathwayPCA is an integrative analysis tool that implements the principal component analysis (PCA) based pathway analysis approaches described in Chen et al. (2008), Chen et al. (2010), and Chen (2011). pathwayPCA allows users to: (1) Test pathway association with binary, continuous, or survival phenotypes. (2) Extract relevant genes in the pathways using the SuperPCA and AES-PCA approaches. (3) Compute principal components (PCs) based on the selected genes. These estimated latent variables represent pathway activities for individual subjects, which can then be used to perform integrative pathway analysis, such as multi-omics analysis. (4) Extract relevant genes that drive pathway significance as well as data corresponding to these relevant genes for additional in-depth analysis. (5) Perform analyses with enhanced computational efficiency with parallel computing and enhanced data safety with S4-class data objects. (6) Analyze studies with complex experimental designs, with multiple covariates, and with interaction effects, e.g., testing whether pathway association with clinical phenotype is different between male and female subjects. Citations: Chen et al. (2008) <https://doi.org/10.1093/bioinformatics/btn458>; Chen et al. (2010) <https://doi.org/10.1002/gepi.20532>; and Chen (2011) <https://doi.org/10.2202/1544-6115.1697>.

Maintained by Gabriel Odom. Last updated 5 months ago.

copynumbervariationdnamethylationgeneexpressionsnptranscriptiongenepredictiongenesetenrichmentgenesignalinggenetargetgenomewideassociationgenomicvariationcellbiologyepigeneticsfunctionalgenomicsgeneticslipidomicsmetabolomicsproteomicssystemsbiologytranscriptomicsclassificationdimensionreductionfeatureextractionprincipalcomponentregressionsurvivalmultiplecomparisonpathways

2.3 match 11 stars 7.74 score 42 scripts

z267xu

loon.tourr:Tour in 'Loon'

Implement tour algorithms in interactive graphical system 'loon'.

Maintained by Zehao Xu. Last updated 3 years ago.

2.2 match 4.48 score 6 scripts 1 dependents