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bioc
syntenet:Inference And Analysis Of Synteny Networks
syntenet can be used to infer synteny networks from whole-genome protein sequences and analyze them. Anchor pairs are detected with the MCScanX algorithm, which was ported to this package with the Rcpp framework for R and C++ integration. Anchor pairs from synteny analyses are treated as an undirected unweighted graph (i.e., a synteny network), and users can perform: i. network clustering; ii. phylogenomic profiling (by identifying which species contain which clusters) and; iii. microsynteny-based phylogeny reconstruction with maximum likelihood.
Maintained by Fabrício Almeida-Silva. Last updated 3 months ago.
softwarenetworkinferencefunctionalgenomicscomparativegenomicsphylogeneticssystemsbiologygraphandnetworkwholegenomenetworkcomparative-genomicsevolutionary-genomicsnetwork-sciencephylogenomicssyntenysynteny-networkcpp
17.4 match 26 stars 6.67 score 12 scripts 1 dependentsdamiendevienne
phylter:Detect and Remove Outliers in Phylogenomics Datasets
Analyzis and filtering of phylogenomics datasets. It takes an input either a collection of gene trees (then transformed to matrices) or directly a collection of gene matrices and performs an iterative process to identify what species in what genes are outliers, and whose elimination significantly improves the concordance between the input matrices. The methods builds upon the Distatis approach (Abdi et al. (2005) <doi:10.1101/2021.09.08.459421>), a generalization of classical multidimensional scaling to multiple distance matrices.
Maintained by Aurélie Siberchicot. Last updated 12 days ago.
phylogenetic-treesphylogeneticsphylogenomicscpp
15.5 match 9 stars 5.91 score 6 scriptslucasnell
jackalope:A Swift, Versatile Phylogenomic and High-Throughput Sequencing Simulator
Simply and efficiently simulates (i) variants from reference genomes and (ii) reads from both Illumina <https://www.illumina.com/> and Pacific Biosciences (PacBio) <https://www.pacb.com/> platforms. It can either read reference genomes from FASTA files or simulate new ones. Genomic variants can be simulated using summary statistics, phylogenies, Variant Call Format (VCF) files, and coalescent simulations—the latter of which can include selection, recombination, and demographic fluctuations. 'jackalope' can simulate single, paired-end, or mate-pair Illumina reads, as well as PacBio reads. These simulations include sequencing errors, mapping qualities, multiplexing, and optical/polymerase chain reaction (PCR) duplicates. Simulating Illumina sequencing is based on ART by Huang et al. (2012) <doi:10.1093/bioinformatics/btr708>. PacBio sequencing simulation is based on SimLoRD by Stöcker et al. (2016) <doi:10.1093/bioinformatics/btw286>. All outputs can be written to standard file formats.
Maintained by Lucas A. Nell. Last updated 1 years ago.
zlibopenblascurlbzip2xz-utilscpp
2.9 match 8 stars 5.28 score 24 scriptseallman
MSCsimtester:Tests of Multispecies Coalescent Gene Tree Simulator Output
Statistical tests for validating multispecies coalescent gene tree simulators, using pairwise distances and rooted triple counts. Background is given by Allman, Banos, and Rhodes (2019) <arXiv:1908.01424>.
Maintained by Elizabeth Allman. Last updated 3 years ago.
1.7 match 1.00 score 1 scripts