Showing 66 of total 66 results (show query)

bioc

BiocGenerics:S4 generic functions used in Bioconductor

The package defines many S4 generic functions used in Bioconductor.

Maintained by Hervรฉ Pagรจs. Last updated 2 months ago.

infrastructurebioconductor-packagecore-package

12 stars 14.22 score 612 scripts 2.2k dependents

alexiosg

rugarch:Univariate GARCH Models

ARFIMA, in-mean, external regressors and various GARCH flavors, with methods for fit, forecast, simulation, inference and plotting.

Maintained by Alexios Galanos. Last updated 3 months ago.

cpp

26 stars 12.25 score 1.3k scripts 16 dependents

mclements

rstpm2:Smooth Survival Models, Including Generalized Survival Models

R implementation of generalized survival models (GSMs), smooth accelerated failure time (AFT) models and Markov multi-state models. For the GSMs, g(S(t|x))=eta(t,x) for a link function g, survival S at time t with covariates x and a linear predictor eta(t,x). The main assumption is that the time effect(s) are smooth <doi:10.1177/0962280216664760>. For fully parametric models with natural splines, this re-implements Stata's 'stpm2' function, which are flexible parametric survival models developed by Royston and colleagues. We have extended the parametric models to include any smooth parametric smoothers for time. We have also extended the model to include any smooth penalized smoothers from the 'mgcv' package, using penalized likelihood. These models include left truncation, right censoring, interval censoring, gamma frailties and normal random effects <doi:10.1002/sim.7451>, and copulas. For the smooth AFTs, S(t|x) = S_0(t*eta(t,x)), where the baseline survival function S_0(t)=exp(-exp(eta_0(t))) is modelled for natural splines for eta_0, and the time-dependent cumulative acceleration factor eta(t,x)=\int_0^t exp(eta_1(u,x)) du for log acceleration factor eta_1(u,x). The Markov multi-state models allow for a range of models with smooth transitions to predict transition probabilities, length of stay, utilities and costs, with differences, ratios and standardisation.

Maintained by Mark Clements. Last updated 5 months ago.

fortranopenblascpp

27 stars 11.09 score 137 scripts 52 dependents

bioc

ropls:PCA, PLS(-DA) and OPLS(-DA) for multivariate analysis and feature selection of omics data

Latent variable modeling with Principal Component Analysis (PCA) and Partial Least Squares (PLS) are powerful methods for visualization, regression, classification, and feature selection of omics data where the number of variables exceeds the number of samples and with multicollinearity among variables. Orthogonal Partial Least Squares (OPLS) enables to separately model the variation correlated (predictive) to the factor of interest and the uncorrelated (orthogonal) variation. While performing similarly to PLS, OPLS facilitates interpretation. Successful applications of these chemometrics techniques include spectroscopic data such as Raman spectroscopy, nuclear magnetic resonance (NMR), mass spectrometry (MS) in metabolomics and proteomics, but also transcriptomics data. In addition to scores, loadings and weights plots, the package provides metrics and graphics to determine the optimal number of components (e.g. with the R2 and Q2 coefficients), check the validity of the model by permutation testing, detect outliers, and perform feature selection (e.g. with Variable Importance in Projection or regression coefficients). The package can be accessed via a user interface on the Workflow4Metabolomics.org online resource for computational metabolomics (built upon the Galaxy environment).

Maintained by Etienne A. Thevenot. Last updated 5 months ago.

regressionclassificationprincipalcomponenttranscriptomicsproteomicsmetabolomicslipidomicsmassspectrometryimmunooncology

7.55 score 210 scripts 8 dependents

cran

fGarch:Rmetrics - Autoregressive Conditional Heteroskedastic Modelling

Analyze and model heteroskedastic behavior in financial time series.

Maintained by Georgi N. Boshnakov. Last updated 1 years ago.

fortran

7 stars 6.33 score 51 dependents

anainesvs

pedigreemm:Pedigree-Based Mixed-Effects Models

Fit pedigree-based mixed-effects models.

Maintained by Ana Ines Vazquez. Last updated 1 years ago.

1 stars 5.42 score 87 scripts 2 dependents

chrisaddy

rrr:Reduced-Rank Regression

Reduced-rank regression, diagnostics and graphics.

Maintained by Chris Addy. Last updated 8 years ago.

10 stars 5.06 score 23 scripts

bioc

frma:Frozen RMA and Barcode

Preprocessing and analysis for single microarrays and microarray batches.

Maintained by Matthew N. McCall. Last updated 5 months ago.

softwaremicroarraypreprocessing

4.72 score 87 scripts 1 dependents

flr

AAP:Aarts and Poos Stock Assessment Model that Estimates Bycatch

FLR version of Aarts and Poos stock assessment model.

Maintained by Iago Mosqueira. Last updated 1 years ago.

2.70 score 5 scripts