Showing 171 of total 171 results (show query)

miraisolutions

XLConnect:Excel Connector for R

Provides comprehensive functionality to read, write and format Excel data.

Maintained by Martin Studer. Last updated 30 days ago.

cross-platformexcelr-languagexlconnectopenjdk

130 stars 12.17 score 1.2k scripts 1 dependents

bioc

destiny:Creates diffusion maps

Create and plot diffusion maps.

Maintained by Philipp Angerer. Last updated 4 months ago.

cellbiologycellbasedassaysclusteringsoftwarevisualizationdiffusion-mapsdimensionality-reductioncpp

82 stars 11.44 score 792 scripts 1 dependents

r-forge

distr:Object Oriented Implementation of Distributions

S4-classes and methods for distributions.

Maintained by Peter Ruckdeschel. Last updated 2 months ago.

8.77 score 327 scripts 32 dependents

bioc

ropls:PCA, PLS(-DA) and OPLS(-DA) for multivariate analysis and feature selection of omics data

Latent variable modeling with Principal Component Analysis (PCA) and Partial Least Squares (PLS) are powerful methods for visualization, regression, classification, and feature selection of omics data where the number of variables exceeds the number of samples and with multicollinearity among variables. Orthogonal Partial Least Squares (OPLS) enables to separately model the variation correlated (predictive) to the factor of interest and the uncorrelated (orthogonal) variation. While performing similarly to PLS, OPLS facilitates interpretation. Successful applications of these chemometrics techniques include spectroscopic data such as Raman spectroscopy, nuclear magnetic resonance (NMR), mass spectrometry (MS) in metabolomics and proteomics, but also transcriptomics data. In addition to scores, loadings and weights plots, the package provides metrics and graphics to determine the optimal number of components (e.g. with the R2 and Q2 coefficients), check the validity of the model by permutation testing, detect outliers, and perform feature selection (e.g. with Variable Importance in Projection or regression coefficients). The package can be accessed via a user interface on the Workflow4Metabolomics.org online resource for computational metabolomics (built upon the Galaxy environment).

Maintained by Etienne A. Thevenot. Last updated 5 months ago.

regressionclassificationprincipalcomponenttranscriptomicsproteomicsmetabolomicslipidomicsmassspectrometryimmunooncology

7.55 score 210 scripts 8 dependents

kornl

gMCP:Graph Based Multiple Comparison Procedures

Functions and a graphical user interface for graphical described multiple test procedures.

Maintained by Kornelius Rohmeyer. Last updated 1 years ago.

openjdk

10 stars 7.31 score 105 scripts 2 dependents

r-forge

distrMod:Object Oriented Implementation of Probability Models

Implements S4 classes for probability models based on packages 'distr' and 'distrEx'.

Maintained by Peter Ruckdeschel. Last updated 2 months ago.

6.60 score 139 scripts 6 dependents

bioc

GeneOverlap:Test and visualize gene overlaps

Test two sets of gene lists and visualize the results.

Maintained by Antรณnio Miguel de Jesus Domingues, Max-Planck Institute for Cell Biology and Genetics. Last updated 5 months ago.

multiplecomparisonvisualization

6.46 score 266 scripts

bioc

qusage:qusage: Quantitative Set Analysis for Gene Expression

This package is an implementation the Quantitative Set Analysis for Gene Expression (QuSAGE) method described in (Yaari G. et al, Nucl Acids Res, 2013). This is a novel Gene Set Enrichment-type test, which is designed to provide a faster, more accurate, and easier to understand test for gene expression studies. qusage accounts for inter-gene correlations using the Variance Inflation Factor technique proposed by Wu et al. (Nucleic Acids Res, 2012). In addition, rather than simply evaluating the deviation from a null hypothesis with a single number (a P value), qusage quantifies gene set activity with a complete probability density function (PDF). From this PDF, P values and confidence intervals can be easily extracted. Preserving the PDF also allows for post-hoc analysis (e.g., pair-wise comparisons of gene set activity) while maintaining statistical traceability. Finally, while qusage is compatible with individual gene statistics from existing methods (e.g., LIMMA), a Welch-based method is implemented that is shown to improve specificity. The QuSAGE package also includes a mixed effects model implementation, as described in (Turner JA et al, BMC Bioinformatics, 2015), and a meta-analysis framework as described in (Meng H, et al. PLoS Comput Biol. 2019). For questions, contact Chris Bolen (cbolen1@gmail.com) or Steven Kleinstein (steven.kleinstein@yale.edu)

Maintained by Christopher Bolen. Last updated 5 months ago.

genesetenrichmentmicroarrayrnaseqsoftwareimmunooncology

5.65 score 185 scripts 1 dependents

r-forge

distrSim:Simulation Classes Based on Package 'distr'

S4-classes for setting up a coherent framework for simulation within the distr family of packages.

Maintained by Peter Ruckdeschel. Last updated 2 months ago.

4.16 score 7 scripts 3 dependents

villegar

scrappy:A Simple Web Scraper

A group of functions to scrape data from different websites, for academic purposes.

Maintained by Roberto Villegas-Diaz. Last updated 1 years ago.

4 stars 3.30 score

jleydold

rstream:Streams of Random Numbers

Unified object oriented interface for multiple independent streams of random numbers from different sources.

Maintained by Josef Leydold. Last updated 2 years ago.

2.69 score 54 scripts 3 dependents