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bioc

mina:Microbial community dIversity and Network Analysis

An increasing number of microbiome datasets have been generated and analyzed with the help of rapidly developing sequencing technologies. At present, analysis of taxonomic profiling data is mainly conducted using composition-based methods, which ignores interactions between community members. Besides this, a lack of efficient ways to compare microbial interaction networks limited the study of community dynamics. To better understand how community diversity is affected by complex interactions between its members, we developed a framework (Microbial community dIversity and Network Analysis, mina), a comprehensive framework for microbial community diversity analysis and network comparison. By defining and integrating network-derived community features, we greatly reduce noise-to-signal ratio for diversity analyses. A bootstrap and permutation-based method was implemented to assess community network dissimilarities and extract discriminative features in a statistically principled way.

Maintained by Rui Guan. Last updated 5 months ago.

softwareworkflowstepcpp

5 stars 4.85 score 14 scripts

bioc

ChIPXpress:ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles

ChIPXpress takes as input predicted TF bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target.

Maintained by George Wu. Last updated 5 months ago.

chipchipchipseq

3.78 score 2 scripts

jaehyunparkbiostat

fusedMGM:Implementation of Fused MGM to Infer 2-Class Networks

Implementation of fused Markov graphical model (FMGM; Park and Won, 2022). The functions include building mixed graphical model (MGM) objects from data, inference of networks using FMGM, stable edge-specific penalty selection (StEPS) for the determination of penalization parameters, and the visualization. For details, please refer to Park and Won (2022) <doi:10.48550/arXiv.2208.14959>.

Maintained by Jaehyun Park. Last updated 6 months ago.

1.00 score

cran

bigtabulate:Table, Apply, and Split Functionality for Matrix and 'big.matrix' Objects

Extend the bigmemory package with 'table', 'tapply', and 'split' support for 'big.matrix' objects. The functions may also be used with native R matrices for improving speed and memory-efficiency.

Maintained by Michael J. Kane. Last updated 3 years ago.

cpp

1.00 score

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