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trio:Testing of SNPs and SNP Interactions in Case-Parent Trio Studies
Testing SNPs and SNP interactions with a genotypic TDT. This package furthermore contains functions for computing pairwise values of LD measures and for identifying LD blocks, as well as functions for setting up matched case pseudo-control genotype data for case-parent trios in order to run trio logic regression, for imputing missing genotypes in trios, for simulating case-parent trios with disease risk dependent on SNP interaction, and for power and sample size calculation in trio data.
Maintained by Holger Schwender. Last updated 3 months ago.
snpgeneticvariabilitymicroarraygenetics
4.36 score 19 scriptsbioc
logicFS:Identification of SNP Interactions
Identification of interactions between binary variables using Logic Regression. Can, e.g., be used to find interesting SNP interactions. Contains also a bagging version of logic regression for classification.
Maintained by Holger Schwender. Last updated 5 months ago.
3.60 score 8 scriptscran
LogicForest:Logic Forest
Two classification ensemble methods based on logic regression models. LogForest() uses a bagging approach to construct an ensemble of logic regression models. LBoost() uses a combination of boosting and cross-validation to construct an ensemble of logic regression models. Both methods are used for classification of binary responses based on binary predictors and for identification of important variables and variable interactions predictive of a binary outcome. Wolf, B.J., Slate, E.H., Hill, E.G. (2010) <doi:10.1093/bioinformatics/btq354>.
Maintained by Melica Nikahd. Last updated 1 years ago.
1 stars 2.00 score