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ranger:A Fast Implementation of Random Forests

A fast implementation of Random Forests, particularly suited for high dimensional data. Ensembles of classification, regression, survival and probability prediction trees are supported. Data from genome-wide association studies can be analyzed efficiently. In addition to data frames, datasets of class 'gwaa.data' (R package 'GenABEL') and 'dgCMatrix' (R package 'Matrix') can be directly analyzed.

Maintained by Marvin N. Wright. Last updated 5 months ago.

cpp

783 stars 16.22 score 9.2k scripts 189 dependents

cran

cmprsk:Subdistribution Analysis of Competing Risks

Estimation, testing and regression modeling of subdistribution functions in competing risks, as described in Gray (1988), A class of K-sample tests for comparing the cumulative incidence of a competing risk, Ann. Stat. 16:1141-1154 <DOI:10.1214/aos/1176350951>, and Fine JP and Gray RJ (1999), A proportional hazards model for the subdistribution of a competing risk, JASA, 94:496-509, <DOI:10.1080/01621459.1999.10474144>.

Maintained by Bob Gray. Last updated 10 months ago.

fortran

3 stars 6.07 score 65 dependents

bioc

clevRvis:Visualization Techniques for Clonal Evolution

clevRvis provides a set of visualization techniques for clonal evolution. These include shark plots, dolphin plots and plaice plots. Algorithms for time point interpolation as well as therapy effect estimation are provided. Phylogeny-aware color coding is implemented. A shiny-app for generating plots interactively is additionally provided.

Maintained by Sarah Sandmann. Last updated 5 months ago.

softwareshinyappsvisualization

6 stars 4.78 score 2 scripts

bioc

RTCA:Open-source toolkit to analyse data from xCELLigence System (RTCA)

Import, analyze and visualize data from Roche(R) xCELLigence RTCA systems. The package imports real-time cell electrical impedance data into R. As an alternative to commercial software shipped along the system, the Bioconductor package RTCA provides several unique transformation (normalization) strategies and various visualization tools.

Maintained by Jitao David Zhang. Last updated 5 months ago.

immunooncologycellbasedassaysinfrastructurevisualizationtimecourse

4.60 score 4 scripts

bips-hb

blockForest:Block Forests: Random Forests for Blocks of Clinical and Omics Covariate Data

A random forest variant 'block forest' ('BlockForest') tailored to the prediction of binary, survival and continuous outcomes using block-structured covariate data, for example, clinical covariates plus measurements of a certain omics data type or multi-omics data, that is, data for which measurements of different types of omics data and/or clinical data for each patient exist. Examples of different omics data types include gene expression measurements, mutation data and copy number variation measurements. Block forest are presented in Hornung & Wright (2019). The package includes four other random forest variants for multi-omics data: 'RandomBlock', 'BlockVarSel', 'VarProb', and 'SplitWeights'. These were also considered in Hornung & Wright (2019), but performed worse than block forest in their comparison study based on 20 real multi-omics data sets. Therefore, we recommend to use block forest ('BlockForest') in applications. The other random forest variants can, however, be consulted for academic purposes, for example, in the context of further methodological developments. Reference: Hornung, R. & Wright, M. N. (2019) Block Forests: random forests for blocks of clinical and omics covariate data. BMC Bioinformatics 20:358. <doi:10.1186/s12859-019-2942-y>.

Maintained by Marvin N. Wright. Last updated 2 years ago.

cpp

7 stars 4.52 score 47 scripts

mnwright

bnnSurvival:Bagged k-Nearest Neighbors Survival Prediction

Implements a bootstrap aggregated (bagged) version of the k-nearest neighbors survival probability prediction method (Lowsky et al. 2013). In addition to the bootstrapping of training samples, the features can be subsampled in each baselearner to break the correlation between them. The Rcpp package is used to speed up the computation.

Maintained by Marvin N. Wright. Last updated 8 years ago.

cpp

1 stars 2.70 score 5 scripts

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