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thie1e
cutpointr:Determine and Evaluate Optimal Cutpoints in Binary Classification Tasks
Estimate cutpoints that optimize a specified metric in binary classification tasks and validate performance using bootstrapping. Some methods for more robust cutpoint estimation are supported, e.g. a parametric method assuming normal distributions, bootstrapped cutpoints, and smoothing of the metric values per cutpoint using Generalized Additive Models. Various plotting functions are included. For an overview of the package see Thiele and Hirschfeld (2021) <doi:10.18637/jss.v098.i11>.
Maintained by Christian Thiele. Last updated 4 months ago.
bootstrappingcutpoint-optimizationroc-curvecpp
88 stars 10.44 score 322 scripts 1 dependentsbioc
EpiCompare:Comparison, Benchmarking & QC of Epigenomic Datasets
EpiCompare is used to compare and analyse epigenetic datasets for quality control and benchmarking purposes. The package outputs an HTML report consisting of three sections: (1. General metrics) Metrics on peaks (percentage of blacklisted and non-standard peaks, and peak widths) and fragments (duplication rate) of samples, (2. Peak overlap) Percentage and statistical significance of overlapping and non-overlapping peaks. Also includes upset plot and (3. Functional annotation) functional annotation (ChromHMM, ChIPseeker and enrichment analysis) of peaks. Also includes peak enrichment around TSS.
Maintained by Hiranyamaya Dash. Last updated 2 months ago.
epigeneticsgeneticsqualitycontrolchipseqmultiplecomparisonfunctionalgenomicsatacseqdnaseseqbenchmarkbenchmarkingbioconductorbioconductor-packagecomparisonhtmlinteractive-reporting
15 stars 7.49 score 46 scripts