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insightsengineering
rbmi:Reference Based Multiple Imputation
Implements standard and reference based multiple imputation methods for continuous longitudinal endpoints (Gower-Page et al. (2022) <doi:10.21105/joss.04251>). In particular, this package supports deterministic conditional mean imputation and jackknifing as described in Wolbers et al. (2022) <doi:10.1002/pst.2234>, Bayesian multiple imputation as described in Carpenter et al. (2013) <doi:10.1080/10543406.2013.834911>, and bootstrapped maximum likelihood imputation as described in von Hippel and Bartlett (2021) <doi: 10.1214/20-STS793>.
Maintained by Isaac Gravestock. Last updated 1 months ago.
18 stars 8.76 score 33 scripts 1 dependents
fhdsl
metricminer:Mine Metrics from Common Places on the Web
Mine metrics on common places on the web through the power of their APIs (application programming interfaces). It also helps make the data in a format that is easily used for a dashboard or other purposes. There is an associated dashboard template and tutorials that are underdevelopment that help you fully utilize 'metricminer'.
Maintained by Candace Savonen. Last updated 1 days ago.
2 stars 6.18 score 21 scripts
plantandfoodresearch
hidecan:Create HIDECAN Plots for Visualising Genome-Wide Association Studies and Differential Expression Results
Generates HIDECAN plots that summarise and combine the results of genome-wide association studies (GWAS) and transcriptomics differential expression analyses (DE), along with manually curated candidate genes of interest. The HIDECAN plot is presented in: Angelin-Bonnet, O., Vignes, M., Biggs, P. J., Baldwin, S., & Thomson, S. (2023). Visual integration of GWAS and differential expression results with the hidecan R package. bioRxiv, 2023-03.
Maintained by Olivia Angelin-Bonnet. Last updated 13 days ago.
7 stars 5.95 score 14 scripts 1 dependents
roaldarbol
animovement:An R toolbox for analysing animal movement across space and time
An R toolbox for analysing animal movement across space and time.
Maintained by Mikkel Roald-Arbøl. Last updated 3 months ago.
animal-behaviouranimal-movementneuroethologyneuroscience
10 stars 4.74 score 8 scripts
tacazares
SeedMatchR:Find Matches to Canonical SiRNA Seeds in Genomic Features
On-target gene knockdown using siRNA ideally results from binding fully complementary regions in mRNA transcripts to induce cleavage. Off-target siRNA gene knockdown can occur through several modes, one being a seed-mediated mechanism mimicking miRNA gene regulation. Seed-mediated off-target effects occur when the ~8 nucleotides at the 5’ end of the guide strand, called a seed region, bind the 3’ untranslated regions of mRNA, causing reduced translation. Experiments using siRNA knockdown paired with RNA-seq can be used to detect siRNA sequences with potential off-target effects driven by the seed region. 'SeedMatchR' provides tools for exploring and detecting potential seed-mediated off-target effects of siRNA in RNA-seq experiments. 'SeedMatchR' is designed to extend current differential expression analysis tools, such as 'DESeq2', by annotating results with predicted seed matches. Using publicly available data, we demonstrate the ability of 'SeedMatchR' to detect cumulative changes in differential gene expression attributed to siRNA seed regions.
Maintained by Tareian Cazares. Last updated 1 years ago.
deseq2-analysismirnarna-seqsirnatranscriptomics
7 stars 4.54 score 7 scripts
yuepan027
scpoisson:Single Cell Poisson Probability Paradigm
Useful to visualize the Poissoneity (an independent Poisson statistical framework, where each RNA measurement for each cell comes from its own independent Poisson distribution) of Unique Molecular Identifier (UMI) based single cell RNA sequencing (scRNA-seq) data, and explore cell clustering based on model departure as a novel data representation.
Maintained by Yue Pan. Last updated 3 years ago.
2.70 score 4 scripts