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openpharma
crmPack:Object-Oriented Implementation of CRM Designs
Implements a wide range of model-based dose escalation designs, ranging from classical and modern continual reassessment methods (CRMs) based on dose-limiting toxicity endpoints to dual-endpoint designs taking into account a biomarker/efficacy outcome. The focus is on Bayesian inference, making it very easy to setup a new design with its own JAGS code. However, it is also possible to implement 3+3 designs for comparison or models with non-Bayesian estimation. The whole package is written in a modular form in the S4 class system, making it very flexible for adaptation to new models, escalation or stopping rules. Further details are presented in Sabanes Bove et al. (2019) <doi:10.18637/jss.v089.i10>.
Maintained by Daniel Sabanes Bove. Last updated 2 months ago.
21 stars 7.76 score 208 scripts
selkamand
assertions:Simple Assertions for Beautiful and Customisable Error Messages
Provides simple assertions with sensible defaults and customisable error messages. It offers convenient assertion call wrappers and a general assert function that can handle any condition. Default error messages are user friendly and easily customized with inline code evaluation and styling powered by the 'cli' package.
Maintained by Sam El-Kamand. Last updated 4 months ago.
3 stars 6.84 score 172 scripts 3 dependents