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lbau7
baskexact:Analytical Calculation of Basket Trial Operating Characteristics
Analytically calculates the operating characteristics of single-stage and two-stage basket trials with equal sample sizes using the power prior design by Baumann et al. (2024) <doi:10.48550/arXiv.2309.06988> and the design by Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>.
Maintained by Lukas Baumann. Last updated 8 months ago.
2 stars 5.22 score 11 scriptsimbi-heidelberg
blindrecalc:Blinded Sample Size Recalculation
Computation of key characteristics and plots for blinded sample size recalculation. Continuous as well as binary endpoints are supported in superiority and non-inferiority trials. See Baumann, Pilz, Kieser (2022) <doi:10.32614/RJ-2022-001> for a detailed description. The implemented methods include the approaches by Lu, K. (2019) <doi:10.1002/pst.1737>, Kieser, M. and Friede, T. (2000) <doi:10.1002/(SICI)1097-0258(20000415)19:7%3C901::AID-SIM405%3E3.0.CO;2-L>, Friede, T. and Kieser, M. (2004) <doi:10.1002/pst.140>, Friede, T., Mitchell, C., Mueller-Veltern, G. (2007) <doi:10.1002/bimj.200610373>, and Friede, T. and Kieser, M. (2011) <doi:10.3414/ME09-01-0063>.
Maintained by Lukas Baumann. Last updated 1 years ago.
5 stars 3.40 score 10 scriptslbau7
basksim:Simulation-Based Calculation of Basket Trial Operating Characteristics
Provides a unified syntax for the simulation-based comparison of different single-stage basket trial designs with a binary endpoint and equal sample sizes in all baskets. Methods include the designs by Baumann et al. (2024) <doi:10.48550/arXiv.2309.06988>, Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>, Berry et al. (2020) <doi:10.1177/1740774513497539>, Neuenschwander et al. (2016) <doi:10.1002/pst.1730> and Psioda et al. (2021) <doi:10.1093/biostatistics/kxz014>. For the latter three designs, the functions are mostly wrappers for functions provided by the packages 'bhmbasket' and 'bmabasket'.
Maintained by Lukas Baumann. Last updated 12 months ago.
1 stars 3.28 score 19 scripts