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SimInf:A Framework for Data-Driven Stochastic Disease Spread Simulations
Provides an efficient and very flexible framework to conduct data-driven epidemiological modeling in realistic large scale disease spread simulations. The framework integrates infection dynamics in subpopulations as continuous-time Markov chains using the Gillespie stochastic simulation algorithm and incorporates available data such as births, deaths and movements as scheduled events at predefined time-points. Using C code for the numerical solvers and 'OpenMP' (if available) to divide work over multiple processors ensures high performance when simulating a sample outcome. One of our design goals was to make the package extendable and enable usage of the numerical solvers from other R extension packages in order to facilitate complex epidemiological research. The package contains template models and can be extended with user-defined models. For more details see the paper by Widgren, Bauer, Eriksson and Engblom (2019) <doi:10.18637/jss.v091.i12>. The package also provides functionality to fit models to time series data using the Approximate Bayesian Computation Sequential Monte Carlo ('ABC-SMC') algorithm of Toni and others (2009) <doi:10.1098/rsif.2008.0172>.
Maintained by Stefan Widgren. Last updated 17 days ago.
data-drivenepidemiologyhigh-performance-computingmarkov-chainmathematical-modellinggslopenmp
35 stars 10.09 score 227 scriptscran
MariNET:Build Network Based on Linear Mixed Models from EHRs
Analyzing longitudinal clinical data from Electronic Health Records (EHRs) using linear mixed models (LMM) and visualizing the results as networks. It includes functions for fitting LMM, normalizing adjacency matrices, and comparing networks. The package is designed for researchers in clinical and biomedical fields who need to model longitudinal data and explore relationships between variables For more details see Bates et al. (2015) <doi:10.18637/jss.v067.i01>.
Maintained by Vargas-Fernández Marina. Last updated 8 days ago.
2.00 score