flippant:Dithionite Scramblase Assay Analysis
The lipid scrambling activity of protein extracts and purified scramblases is often determined using a
fluorescence-based assay involving many manual steps. flippant
offers an integrated solution for the analysis and
publication-grade graphical presentation of dithionite
scramblase assays, as well as a platform for review,
dissemination and extension of the strategies it employs. The
package's name derives from a play on the fact that lipid
scrambling is also sometimes referred to as 'flipping'. The
package is originally published as Cotton, R.J., Ploier, B.,
Goren, M.A., Menon, A.K., and Graumann, J. (2017). "flippant–An
R package for the automated analysis of fluorescence-based
scramblase assays." BMC Bioinformatics 18, 146.
<DOI:10.1186/s12859-017-1542-y>.
