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bioc
GBScleanR:Error correction tool for noisy genotyping by sequencing (GBS) data
GBScleanR is a package for quality check, filtering, and error correction of genotype data derived from next generation sequcener (NGS) based genotyping platforms. GBScleanR takes Variant Call Format (VCF) file as input. The main function of this package is `estGeno()` which estimates the true genotypes of samples from given read counts for genotype markers using a hidden Markov model with incorporating uneven observation ratio of allelic reads. This implementation gives robust genotype estimation even in noisy genotype data usually observed in Genotyping-By-Sequnencing (GBS) and similar methods, e.g. RADseq. The current implementation accepts genotype data of a diploid population at any generation of multi-parental cross, e.g. biparental F2 from inbred parents, biparental F2 from outbred parents, and 8-way recombinant inbred lines (8-way RILs) which can be refered to as MAGIC population.
Maintained by Tomoyuki Furuta. Last updated 15 days ago.
geneticvariabilitysnpgeneticshiddenmarkovmodelsequencingqualitycontrolcpp
4 stars 5.92 score 6 scripts
christinaheinze
CompareCausalNetworks:Interface to Diverse Estimation Methods of Causal Networks
Unified interface for the estimation of causal networks, including the methods 'backShift' (from package 'backShift'), 'bivariateANM' (bivariate additive noise model), 'bivariateCAM' (bivariate causal additive model), 'CAM' (causal additive model) (from package 'CAM'; the package is temporarily unavailable on the CRAN repository; formerly available versions can be obtained from the archive), 'hiddenICP' (invariant causal prediction with hidden variables), 'ICP' (invariant causal prediction) (from package 'InvariantCausalPrediction'), 'GES' (greedy equivalence search), 'GIES' (greedy interventional equivalence search), 'LINGAM', 'PC' (PC Algorithm), 'FCI' (fast causal inference), 'RFCI' (really fast causal inference) (all from package 'pcalg') and regression.
Maintained by Christina Heinze-Deml. Last updated 5 years ago.
22 stars 3.90 score 12 scripts 1 dependents