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bioc
ELMER:Inferring Regulatory Element Landscapes and Transcription Factor Networks Using Cancer Methylomes
ELMER is designed to use DNA methylation and gene expression from a large number of samples to infere regulatory element landscape and transcription factor network in primary tissue.
Maintained by Tiago Chedraoui Silva. Last updated 5 months ago.
dnamethylationgeneexpressionmotifannotationsoftwaregeneregulationtranscriptionnetwork
7.42 score 176 scripts
pboutros
SeqKat:Detection of Kataegis
Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 <doi:10.1101/287839>.
Maintained by Paul C. Boutros. Last updated 5 years ago.
2.11 score 13 scripts