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bioc
SPsimSeq:Semi-parametric simulation tool for bulk and single-cell RNA sequencing data
SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.
Maintained by Joris Meys. Last updated 5 months ago.
geneexpressionrnaseqsinglecellsequencingdnaseq
10 stars 7.14 score 29 scripts 1 dependents