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bioc

DESeq2:Differential gene expression analysis based on the negative binomial distribution

Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution.

Maintained by Michael Love. Last updated 25 days ago.

sequencing rnaseq chipseq geneexpression transcription normalization differentialexpression bayesian regression principalcomponent clustering immunooncology openblas cpp

375 stars 16.11 score 17k scripts 115 dependents

bioc

BindingSiteFinder:Binding site defintion based on iCLIP data

Precise knowledge on the binding sites of an RNA-binding protein (RBP) is key to understand (post-) transcriptional regulatory processes. Here we present a workflow that describes how exact binding sites can be defined from iCLIP data. The package provides functions for binding site definition and result visualization. For details please see the vignette.

Maintained by Mirko Brüggemann. Last updated 11 days ago.

sequencing geneexpression generegulation functionalgenomics coverage dataimport binding-site-classification binding-sites bioconductor-package iclip rna-binding-proteins

6 stars 5.80 score 3 scripts