Showing 1 of total 1 results (show query)
bioc
SimFFPE:NGS Read Simulator for FFPE Tissue
The NGS (Next-Generation Sequencing) reads from FFPE (Formalin-Fixed Paraffin-Embedded) samples contain numerous artifact chimeric reads (ACRS), which can lead to false positive structural variant calls. These ACRs are derived from the combination of two single-stranded DNA (ss-DNA) fragments with short reverse complementary regions (SRCRs). This package simulates these artifact chimeric reads as well as normal reads for FFPE samples on the whole genome / several chromosomes / large regions.
Maintained by Lanying Wei. Last updated 5 months ago.
sequencingalignmentmultiplecomparisonsequencematchingdataimport
3.30 score 1 scripts