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billdenney
PKNCA:Perform Pharmacokinetic Non-Compartmental Analysis
Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.
Maintained by Bill Denney. Last updated 1 months ago.
ncanoncompartmental-analysispharmacokinetics
73 stars 12.53 score 214 scripts 4 dependents
insightsengineering
simIDM:Simulating Oncology Trials using an Illness-Death Model
Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.
Maintained by Alexandra Erdmann. Last updated 1 years ago.
multistate-modelssimulation-engine
13 stars 6.26 score 9 scripts