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bioc
ggmsa:Plot Multiple Sequence Alignment using 'ggplot2'
A visual exploration tool for multiple sequence alignment and associated data. Supports MSA of DNA, RNA, and protein sequences using 'ggplot2'. Multiple sequence alignment can easily be combined with other 'ggplot2' plots, such as phylogenetic tree Visualized by 'ggtree', boxplot, genome map and so on. More features: visualization of sequence logos, sequence bundles, RNA secondary structures and detection of sequence recombinations.
Maintained by Guangchuang Yu. Last updated 3 months ago.
softwarevisualizationalignmentannotationmultiplesequencealignment
210 stars 9.35 score 196 scripts 2 dependents
jlp-bioinf
rnaCrosslinkOO:Analysis of RNA Crosslinking Data
Analysis of RNA crosslinking data for RNA structure prediction. The package is suitable for the analysis of RNA structure cross-linking data and chemical probing data.
Maintained by Jonathan Price. Last updated 2 months ago.
comradespsoralenrna-crosslinkingrna-structurerna-structure-prediction
1 stars 5.08 score 3 scripts
tacazares
SeedMatchR:Find Matches to Canonical SiRNA Seeds in Genomic Features
On-target gene knockdown using siRNA ideally results from binding fully complementary regions in mRNA transcripts to induce cleavage. Off-target siRNA gene knockdown can occur through several modes, one being a seed-mediated mechanism mimicking miRNA gene regulation. Seed-mediated off-target effects occur when the ~8 nucleotides at the 5’ end of the guide strand, called a seed region, bind the 3’ untranslated regions of mRNA, causing reduced translation. Experiments using siRNA knockdown paired with RNA-seq can be used to detect siRNA sequences with potential off-target effects driven by the seed region. 'SeedMatchR' provides tools for exploring and detecting potential seed-mediated off-target effects of siRNA in RNA-seq experiments. 'SeedMatchR' is designed to extend current differential expression analysis tools, such as 'DESeq2', by annotating results with predicted seed matches. Using publicly available data, we demonstrate the ability of 'SeedMatchR' to detect cumulative changes in differential gene expression attributed to siRNA seed regions.
Maintained by Tareian Cazares. Last updated 1 years ago.
deseq2-analysismirnarna-seqsirnatranscriptomics
7 stars 4.54 score 7 scripts
mohmedsoudy
ggaligner:Visualizing Sequence Alignment by Generating Publication-Ready Plots
Providing publication-ready graphs for Multiple sequence alignment. Moreover, it provides a unique solution for visualizing the multiple sequence alignment without the need to do the alignment in each run which is a big limitation in other available packages.
Maintained by Mohamed Soudy. Last updated 2 years ago.
2.70 score 1 scripts